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Transcript of Biomaterials
biopolymers polymeric biomaterials natural polymer structure any material with biomedical application
in contact withbiological fluids and meet demands of the application biocompatibility units covalently bonded to form larger structures
made up of complex structural units; primary structure
polypeptides (proteins) - condesation polymers of amino acids
polysaccharides (sugars) - linear bonded polymeric carbohydrate structures
polynucleotides (RNA, DNA) - long polymers composed of 13 or more nucleotide monomers What are Biomaterials? natural or synthesized?
theraputic or diagnostic? physical requirements chemical requirements - readily integrated into body
- chemical nature
and physical texture - medical grande: approved for use in medical applications
- some commercial polymers have small amounts of contaminants
- HDPE used in milk jugs polymer is determined by the naure of the atomic groups and the possibilities for interaction with the body's molecules natural polymer
synthetic polymer natural polymers - biopolymers biopolymers often spontaneously fold into characteristic compact shapes; determines biological functions; protein modeling polyurethane Synthetic Polymers - simpler, more repetitive structures than natural polymers
- only few or no polar groups that can interact with body's aqueous medium
difference in complexity helps the body determine synthetic as foreign uses of polymers Thermoplastics:
polyethylene & polyester
membranes in blood dialysis machines and replacements for blood vessels
Elastomers: flexible tubing for implanted heart pacemakers and catheters
Thermoset plastics: used to fill cavity and orthopedic applications in joint replacement;
must shine ultraviolet lamp to form a harder thermoset polymer