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Team Amazing Grace 2016, Walk to make Cystic Fibrosis HISTORY

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Jamie Voss

on 29 April 2016

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Transcript of Team Amazing Grace 2016, Walk to make Cystic Fibrosis HISTORY

70,000 people including Grace are living with cystic fibrosis, making it the most common fatal genetic disease in the world
70,000 people like Grace are living with cystic fibrosis, making it one of the most common fatal genetic diseases worldwide
But there are still many obstacles to overcome...
Cystic Fibrosis is caused by a mutation in the CFTR gene. This gene codes for a protein that regulates chloride transport out of the cells
When a person inherits a CFTR gene that is mutated from both their mother and their father then they will have cystic fibrosis. Unable to regulate salt transport a thick mucous builds up in the lungs and digestive system
In the lungs, thick mucous reduces oxygen exchange often making it very difficult to breathe. It causes infections that cannot be easily fought by the patients own immune system. These infections cause structural damage to the lungs gradually destroying them
Cystic Fibrosis Canada funds research to improve lung function in CF patients. Today, inhaled saline solutions and steroids help keep airways open and reduce infection.

Antibiotics help lessen damage caused by infections. New ones are needed as resistance emerges
In the digestive system, CF mainly affects the pancreas. The pancreas is an organ that secretes enzymes which aid in digestion and control blood sugar levels. Thick mucous prevents this in CF. People with CF have trouble digesting fats, some proteins and fat soluble vitamins A, D, E and K. Problems become more severe with time and lead to glucose intolerance and insulin-dependent diabetes. The liver can also be affected causing liver disease
Cystic Fibrosis Canada helps provide life saving digestive enzymes so children can grow and absorb nutrients!!
So much has been done already
Several decades ago the average lifespan of someone with CF was 2 ....Today, it is 37. Thanks to the dedication and love of many
Amazing things are happening!!! The Cystic Fibrosis Foundation helped finance the development of 'Kalydeco' by Vertex pharmaceuticals....Released in 2012, it is the first medicine that actually CORRECTS the defective CFTR protein for patients with certain mutations!
In 2013, CFTR gene mutations were actually CORRECTED in cells in culture from a CF patient....

That is why we are
inviting you to
join us for the
Sunday May 29th at the
Metro Toronto Zoo. Come show your love and help raise money to CURE CF

Thank you for adding tomorrows...
Full transcript