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Sickle Cell Anemia

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Jacob Howard

on 3 September 2010

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Transcript of Sickle Cell Anemia

Sickle Cell Anemia Created by Jacob Howard
and Zach Barrett What is Sickle Cell Anemia? Sickle cell is a disease in which the production of Hemo globin is altered to an abnormal rate.
Hemoglobin is a protein composed of globin and heme which binds to red blood cells and gives them their characteristic color as well as transport oxygen throughout the body.
Sickle Cell is given its name due to the characteristic sickle shape of the blood cells of an infected person. Symptoms of Sickle Cell Anemia are as follows: Fatigue
Shortness of breath
Coldness in hands and feet
Pale skin
Chest pain
Sickle Cell Crysis (sudden pain throughout the body)
Weakened immune system Cures There are no widely available complete cures for Sickle Cell
Anemia. However, there are some cures for symptoms and pain: Bone marrow transplants may offer a cure but only in small cases.
Blood transfusions can cure Sickle Cell as well, and are commonly used in slightly worsening cases.
Infection is a leading cause of death from Sickle Cell Anemia. To prevent infections in children and babies:
Daily doses of penicillin
Recieving all regular vaccinations, including meningococcal Created by Jacob Howard
and Zach Barrett Where is Sickle Cell found? Sickle Cell is found in the 15.5th region of the short (p) arm of human chromosome 11. How is it inherited? Most people have two normal hemoglobin genes. But some people have only ONE normal gene, and one sickle hemoglobin theme. This is called Sickle Cell Trait, and will not cause illness or develop into Sickle Cell Disease.
Sickle Cell cannot, only inherited at birth from carriers of the gene. Since the disease cannot be contratcted, it also cannot be lost or altered in any way.
When Sickle Cell Trait does become a problem is when a child inherits two Sickle Cell genes (one from each parent) and is born with Sickle Cell Disease.
While Sickle Cell Trait is nearly harmless and does not cause illness, Sickle Cell Disease is mostly fatal and those infected will show signs of some (if not many) of the symptoms.
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