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Transcranial magnetic stimulation (TMS)
Transcript of Transcranial magnetic stimulation (TMS)
What is TMS?
Based in the Principle of Electromagnetic Induction;
Activates certain brain parts;
Used by neuroscientists and psychiatrists.
The method had as primary purpose the diagnostic/research.
Prof. Anthony T. Barker
Pioneer in Magnetic Stimulation;
Creates the first TMS machine at 1985, in the University of Sheffield, United Kingdom;
Reginald George Bickford
In 1987, Bickford (USA) realized that his patients started to show significant improvement in their mood (humor).
Neurological and psychiatric illnesses treated by TMS:
• Multiple Sclerosis
• Central Motor Disorders
• Motor Neurone Disease
• Spinal Injury
• OCD Obsessive–compulsive disorder
• Bipolar disorder
• Parkinson's disease
History of TMS
Oral Communication Class
Instructor Glen Piskula
CESL - University of Arizona
Transcranial Magnetic Stimulation (TMS)
Principal Works Cited:
Stewart, Lauren; Walsh, Vincent; Frith, UTA; Rothwell, John (2006). "Transcranial Magnetic Stimulation Produces Speech Arrest but Not Song Arrest". Annals of the New York Academy of Sciences 930: 433–5. doi:10.1111/j.1749-6632.2001.tb05762.x . PMID 11458860.
Creutzfeldt, O & Ojemann, G. Neuronal activity in the human lateral temporal lobe. III. Activity changes during music. Experimental brain research. 1989. n.p. <http://www.biomedsearch.com/nih/Neuronal-activity-in-human-lateral/2806443.html>.
A T Barker, R Jalinous, and I L Freeston. “Non-invasive Magnetic Stimulation of Human Motor Cortex.” Lancet 1985.
Bickford RG, Guidi M, Fortesque P, Swenson M. (1987): Magnetic stimulation of human peripheral nerve and brain: Response enhancement by combined magnetoelectrical technique. Neurosurgery 20: 110–116
Avery DH, Claypoole K, Robinson L, Neumaier JF, Dunner DL, Scheele L, Wilson L, Roy-Byrne P: Repetitive transcranial magnetic stimulation in the treatment of medication-resistant depression: preliminary data. J Nerv Ment Dis; 187(2):114-7, 1999.
Geller V, Grisaru N, Abarbanel JM, Lemberg T, Belmaker RH: Slow magnetic stimulation of prefrontal cortex in depression and schizophrenia. Prog Neuro-psychopharmacol & Biol Psychiat; 21:105-110, 1997.
Women & Infants Hospital. "Efficacy of transcranial magnetic stimulation for depression confirmed in new study." ScienceDaily. ScienceDaily, 26 July 2012. <www.sciencedaily.com/releases/2012/07/120726180305.htm>.
Speech: controlled in the bottom of the left frontal lobe called "Broca's area"
Sing: related with the right temporal lobe
TMS became a technique to treat depression
and other psychiatric diseases.
• Neurological research;
• Cortical mapping and brain research;
• Functional assessment of central motor pathways;
• Early diagnosis, assessment and monitoring of nervous disease.
• Amyotrophic lateral sclerosis
• Chronic Pain
• Post-traumatic Stress Disorder
• Cerebrovascular Accident (CVA)
• Major depressive disorder (MDD)
Mental disorder that affects the self-steem (mood);
Associated with dorsolateral prefrontal cortex(DLPFC) and limbic system;
In the depressed brain: blood flow and neuronal activity on the left DLPFC are decreased.
Also a reverse activity occurs between the two hemispheres.
Curiosities about TMS:
How deep in the brain? 20-30mm
Capacitor voltage: 0-3000 V
Coil current: 0-8000A
Pulse duration: 0.1-0.2 ms
Treatment cost: $2000(BR)~$7000(USA)
TMS Machine price ranges from
US$ 30,000 to US$ 40,000