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Epstein-Barr Virus

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Kasey Madigan

on 19 January 2014

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Transcript of Epstein-Barr Virus

Epstein-Barr Virus
Mononucleosis

Where is this Virus found inside and outside of the body?
How the Virus is spread and able to survive?
The virus is transported by saliva. The Virus enters the body and attaches to and is infected into a specialized immune lymphocyte cell or also known as B cells, the virus then takes control of the cells DNA and controls the cell forever. When the cells in the mouth and throat shed off they become parts of saliva, the infected cells are now able to be spread and to infect the next victim.
Symptoms of Mononucleosis
Really Tired
Headache
extremely Sore Throat
Chills
Muscle Aches
Swollen Tonsils
Rash
Jaundice (a yellow tint to the skin or eyes)
Work Cited
http://www.webmd.com/a-to-z-guides/understanding-mononucleosis-symptoms
http://www.doctoroz.com/videos/secret-life-epstein-barr-virus
http://www.cdc.gov/ncidod/diseases/ebv.htm
http://www.prohealth.com/library/showarticle.cfm?libid=18412
http://en.wikipedia.org/wiki/Infectious_mononucleosis


Intro To the Epstein-Barr Virus
The Epstein Barr virus (EBV) is a virus that can cause Mononucleosis, also known as mono, the kissing disease, and glandular fever. The virus itself is about 0.0006mm (120nm) in diameter and is made of a double helix of DNA warped in a capsid which is then surrounded by an envelope. The DNA of this virus contains 85 genes. The outer layer of the envelope is made of glycoproteins, they are important to the infection process of the host cell.
- The Epstein-Barr Virus is for the most part a world wide virus but is mainly found in North America and also Japan.

- The virus is attracted to the cells that line the mouth and throat.
The severity of Mononucleosis
On the rare occasion Mononucleosis of the EBV can cause some serious problems. The main problem to show up is an inflated spleen. If the spleen grows to big it may rupture, this is most likely to happen from playing sports at the time of being ill. Another common problem is in the liver causing a yellow tone to your skin.
How To Avoid and Treat Mononucleosis
- The best ways to avoid it is by not sharing saliva products with anyone; bottles/cans, glasses, plates, eating utensils, lip balm, and kissing.
- Although there is no real treatment for Mononucleosis, plenty of sleep and drinking lots of liquids will improve recovery time as well as taking medication like Advil and Tylenol for the fever and swelling. (Taking Antibiotics will not help cure Mono)
What Is the Virus' relationship with other organisms?
The EBV contains double stranded DNA carrying its genetic information. Being a virus is does not have the reproduction protein making it need to attach and over take lymphatic/epithelial cells (both have to be from human) making them the hosts they need to reproduce and spread.
Exra Into Of the Virus In This Video
Research for a Vaccine
Researchers are getting close to finding a vaccine, they know how the virus takes control and how they hide from the immune cells by; triggering molecular events that turn off key proteins, making infected cells invisible to the natural killer immune cells that seek and destroy EBV-infected cells. "If you can force these invisible proteins to be expressed, then you can render infected cells visible to NKT cells, and defeat the virus. This could be key to making a vaccine that would provide immunity from ever being infected with EBV," says Dr. Rusung Tan a Scientist and Director of the Immunity in Health & Disease.
Historical Facts on Mononucleosis
The first year that symptomatology of infectious mononucleosis was recorded was in 1885, when a Russian pediatrician reported some similar symptoms as Mononucleosis. Another report from a German Pediatrician, Emil Pfeiffer, reporting similar cases and giving it the term 'glandular fever'. In 1920 Thomas Peck Sprunt and Frank Alexander Evans gave it the term 'Infectious Mononucleosis' when they were writing up an article of the symptoms. The Epstein–Barr virus was first identified in Burkitt's lymphoma cells by Michael Anthony Epstein and Yvonne Barr at the University of Bristol in 1964. Then lastly in 1967 they realized the cause of Mononucleosis is the EBV.
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