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In-Vitro Fertilization

Advanced Placement Bio grade 11 presentation
by

Yash Kadaru

on 22 January 2016

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Transcript of In-Vitro Fertilization

InVitro Fertilization
What is InVitro
Fertilization?
A reproductive technique used to fertilize egg cells outside the female’s body. A man's sperm and the woman's egg are combined in a laboratory dish, where fertilization occurs.
The word 'vitro' means 'glass', hence the name 'In Vitro Fertilization'
2000
Need for Assisted
Human Reproduction
SHOW SOME LOVE.
Who benefits from IVF?
How does it work?
Views on IVF
The
desire to have children is universal
; IVF is a successful method that allows couples and single women or men to have a child
biologically related
to them. IVF is now recognized worldwide as an established treatment for infertility.
Over 1.5 million babies conceived through IVF have been born since 1978.
InVitro
Fertilization
Physicians & Scientists
Different
perspectives
Pre- Implantation Genetic Diagnosis (PGD)
Saviour Siblings
Process:
Womans egg is fertilized in a Petri dish at a Laboratory.
After 3 days have gone by they take a part of the cell.
It is screened to see if there is a genetic disorder.
The embryos are then deemed healthy and without the genetic disorder that can potentially kill the baby.
The
healthy
cells are implanted back into the mother.
Only used for parents or children with :
serious life threatening diseases
leukemia,
Huntington’s,
Fragile X ,
Cystic fibrosis,
Thalassemia ,
Diamond Black fan Anemia
pre-implantation tissue typing (PITT)
Canadian law doesn’t allow PGD for traits that
aren’t life threatening
like skin colour, and gender selection.
This process reduces the chances of the parent’s offspring being born with a serious life threatening disease,

Only healthy embryos
are selected to be implanted back into the mother.
medical benefits to the healthy child outweigh unethical concerns of PGD .
Are you going to let your child suffer and die in your arms if you have the technology to create a new life which is invulnerable to genetic defects?
2010
2002 March

Real Life
examples of Kids that have a
Saviour sibling
Case 1 : Child with Fancomi Anemia
A nine year old girl in the UK that had fancomi anemia (which is a blood disorder that
DESTROYS BONE MARROW
)
needed a bone marrow transfusion.
After searching worldwide to find a donor to save her life, the parents had
IVF
BABY
Her new savoir sibling was selected as an EMBRYO after several tests which showed that he had no sign of the disease.
When the child was born they collected the umbilical cord blood which has stem cells that match both children
when the brother turns
1 year old
they will collect
BONE MARROW
from him.
CASE 2: Charlie W.
He was born with
Diamond Black Fan Anemia
which prevents his body from creating red blood cells.
Since he
cannot make red blood cells
Charlie goes through
blood transfusions every 2 weeks
and
daily injections
to keep his blood healthy.
Since Charlie only needed a
stem cell transplant
to help him re-grow the bone marrow, his parents decided to have and
IVF baby
and select a genetic match that would save Charlie’s life.
Now not only do they
have 1 child saved
but they will have
another beautiful life.
Charlie’s Brother Jamie was born free from the disease and was a
tissue match
to his big brother Charlie.
After the doctors collected the
umbilical cord blood
with the
stem cells
and gave them to Charlie,

his bone marrow has shown no traces of Diamond black fan anemia
and he is living a healthy life along with his brother.
Case 3 : The Movie My sisters Keeper
The Movie My sisters Keeper is a great example of a Saviour sibling.
Anna
the
saviour sibling
was created through in virto fertilization and PGD
. She was carefully selected by doctors to be the perfect genetic match for her older sister who suffers from
Leukemia.

As the movie progresses
Anna gives her umbilical cord blood
to her sister
then later she finds out that she needs to
donate a kidney
for her sister
Has to go through
invasive procedures
to help her sister
Why InVitro?
Factors
Some
Many
Few
Ovulation Disorders
Fallopian Tube Blockage
Pelvic Inflammatory Disease/Sexually Transmitted Diseases.
Hormone Imbalance
Smoking
Alchohol & Substance Abuse
Stress & Physcological Factors.
Sexual Dysfunction
Sperm Quality
Age & Weight
Infertility
Infertile Couples
Women who want to raise a child alone
Couples in a same sex relationship
Couples who want to diagnose and avoid genetic disorders
Process:
Government Funding
Quebec is the first Canadian pronvince to help fund IVF treatments
Quebec will fund 3 IVF treatment cycles
Believed to save the province $30 million dollars in health care given to premature babies
Ontario funds three IVF treatments for women with two blocked fallopian tubes
Saviour
Siblings
Couples have children that are biologically related to them.
Allows mothers to experience pregnancy and have a bond with their child.
IVF
parents who want multiple children
Egg Retrieval
Embryo Transfer
Sperm Retrieval
Fertilization & Embryo Development
Ovarian Stimulation
Hormones
2 Months Approx.
By Ailana.S, Yash.G, Tamandeep.K and Melissa.R
Genetically Related Children
Sinful. Playing God is not right.
You have to live with it.
It's your fate.
Infertility
Single Parent
Same Sex Couples
Church
Parent(s)
It's going to cost a lot but having
a baby far outweighs that doesn't it?
How much will it cost?
Emotional Distress
Genetic Defects?
Does my age matter?
I don't want a
miscarriage.
Will it work?
All I want is child of our/my own.
A process where not only the
genes
are made to
match their sibling
but also the
tissue formation
, so that if a transplant is ever needed the sibling can donate an organ and
chances of rejection are reduced
.
Tip
Having a baby of your own!
Going through IVF
70% chance of successful birth.
Oct 11 2007 - CFAS Press Release
Afraid of Multiple Births?
69% were singletons.
95% of multiple births were twins.
Oct 11 2007 - CFAS Press Release
IVF
The Argument
Full transcript