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Transcript of CIPA
(CIPA) What is CIPA? Congenital- since birth
Insensitivity to pain- A person with CIPA cannot feel pain or differentiate even extreme temperatures
Anhidrosis- the body does not sweat CIPA is an extremely rare inherited disorder of the nervous system which prevents the sensation of pain, heat, cold, or any real nerve-related sensations (including feeling the need to urinate); however, patients can still feel pressure.
CIPA is caused by a genetic mutation which prevents the formation of nerve cells which are responsible for transmitting signals of pain, heat, and cold to the brain Cause: CIPA leads to: hyperthermia during hot weather because of inability to sweat
mental retardation as a result of hyperthermia
infection and scarring of the tongue, lips and gums
chronic infections of bones and joints
eye related issues, such as infection due to the sufferers rubbing them too hard, too frequently or scratching them during sleep
multiple scars Differential diagnosis: Congenital insensitivity to pain with anhidrosis may be misdiagnosed for leprosy, based on similar symptoms of severe injuries to the hands and feet. Treatment: Treatments for CIPA do not always work; however, there are some cases where naloxone may be used as a treatment
Naloxone is a chemical that acts within the nervous system of the body by blocking the nervous system from causing the inactions that occur within the group of cells that receives the message to initiate the sensation of pain, heat, or col