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MBG 202 Molecular Biology: Chromosomes
Transcript of MBG 202 Molecular Biology: Chromosomes
Structure and Function
How DNA is stored in the nucleus
Only seen during mitosis/meiosis
Humans have 46 chromosomes
relaxed, unwound DNA --> all the pieces are mixed together like a plate of spaghetti
DNA is usually found in chromatin form in the cell
How does chromatin get wound up into a chromosome?
balls of protein
- the double
helix is wrapped around like a ball of yarn.
8 Histones + DNA are wrapped around each other
3.) Super Coiled:
Nucleosomes wrap around each other
-Like a telephone wire
Organism or cell containing
Chromosomes that pair together, which are the same size and have genes in the same location.
(Not identical - different base pairs)
Each homologous chromosome from the pair is inherited from mom or dad
Chromosomes are numbered in pairs #1 - #23
One strand of the chromosome
Contains the DNA
One chromatid replicates to create 2 sister chromatids
Organism or cell with
, unpaired chromosome
Usually smaller asexual organisms
Sex cells / Gametes: sperm and eggs
Numbered in order from pair #1 to pair #23, decreasing in size
non-sex chromosomes. #1-#22
pair #23 - determine male or female and sexual characteristics
links the sister chromatids
Don't have a matching paired chromosome
sex cells, haploid
Sperm and eggs
body cells, diploid
Identical Sister Chromatids
Ex: Where gene for eye color is
MBG 202: Molecular Biology
by Ferhat Ozturk, Ph.D.