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Sickle Cell Disease

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by

Allexe Glaze

on 25 May 2015

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Transcript of Sickle Cell Disease

What is Sickle Cell Disease?
Sickle Cell Disease is a hereditary blood disorder, characterized by an abnormality in oxygen-carrying hemoglobin molecule in red blood cells, leads to an abnormal rigid, sickle-cell shaped under certain circumstances.
Effects
Shortness of breath
Dizziness
Headaches
Swelling in hands and feet
Paleness, fatigue, and rapid pulse
Chest pain/ Enlarged spleen
Stroke/ Abdominal pain
Cure for SCD?
You can get a Blood and Marrow Stem Cell Transplant. This treatment may offer a cure for a small amount of people.
Normal blood cell vs. Sickle cell
Sickle Cell Trait
SCT is a condition which a child inherits the sickle cell gene mutation from one parent.
So, If both parents have the SCT, there's a 50% chance that one of any child will have SCD, the child inherits the sickle cell gene from one of the parents.
Statistics
Affects 90,000 to 100,000 Americans
SCD occurs among 1 out of every Black/African-American births
SCD occurs among 1 out of 36,000 Hispanic-American births
Sickle Cell Disease
Cause for SCD?
SCD is a genetic condition that's present at birth.
It's inherited when a child receives two sickle cell genes, one from each parent.
Harmful SCT Conditions
Increased pressure in the atmosphere.
Low oxygen levels in the air.
Dehydration
High Altitudes
Diagnosis
SCD is diagnosed with a simple blood test.
Most often found at birth during routine newborn screening tests.
SCD can be diagnosed before birth.
Children with SCD are at an increased of infection & other health problems.
Facts about SCD
SCD is a generic term for a group of genetic disorders characterized by a predominance of hemoglobin S (HB S)
SCD can effect many ethnicities including African, Middle Eastern, Latino, Asian, Indian, etc.
Facts about SCT
SCT is not consdered a disease.
About 1 out of 12 African-Americans has SCT.
Also, about 1 out of every 100 latinos has SCT.
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