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Sickle Cell Disease

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Allexe Glaze

on 25 May 2015

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Transcript of Sickle Cell Disease

What is Sickle Cell Disease?
Sickle Cell Disease is a hereditary blood disorder, characterized by an abnormality in oxygen-carrying hemoglobin molecule in red blood cells, leads to an abnormal rigid, sickle-cell shaped under certain circumstances.
Shortness of breath
Swelling in hands and feet
Paleness, fatigue, and rapid pulse
Chest pain/ Enlarged spleen
Stroke/ Abdominal pain
Cure for SCD?
You can get a Blood and Marrow Stem Cell Transplant. This treatment may offer a cure for a small amount of people.
Normal blood cell vs. Sickle cell
Sickle Cell Trait
SCT is a condition which a child inherits the sickle cell gene mutation from one parent.
So, If both parents have the SCT, there's a 50% chance that one of any child will have SCD, the child inherits the sickle cell gene from one of the parents.
Affects 90,000 to 100,000 Americans
SCD occurs among 1 out of every Black/African-American births
SCD occurs among 1 out of 36,000 Hispanic-American births
Sickle Cell Disease
Cause for SCD?
SCD is a genetic condition that's present at birth.
It's inherited when a child receives two sickle cell genes, one from each parent.
Harmful SCT Conditions
Increased pressure in the atmosphere.
Low oxygen levels in the air.
High Altitudes
SCD is diagnosed with a simple blood test.
Most often found at birth during routine newborn screening tests.
SCD can be diagnosed before birth.
Children with SCD are at an increased of infection & other health problems.
Facts about SCD
SCD is a generic term for a group of genetic disorders characterized by a predominance of hemoglobin S (HB S)
SCD can effect many ethnicities including African, Middle Eastern, Latino, Asian, Indian, etc.
Facts about SCT
SCT is not consdered a disease.
About 1 out of 12 African-Americans has SCT.
Also, about 1 out of every 100 latinos has SCT.
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