Loading presentation...

Present Remotely

Send the link below via email or IM

Copy

Present to your audience

Start remote presentation

  • Invited audience members will follow you as you navigate and present
  • People invited to a presentation do not need a Prezi account
  • This link expires 10 minutes after you close the presentation
  • A maximum of 30 users can follow your presentation
  • Learn more about this feature in our knowledge base article

Do you really want to delete this prezi?

Neither you, nor the coeditors you shared it with will be able to recover it again.

DeleteCancel

Make your likes visible on Facebook?

Connect your Facebook account to Prezi and let your likes appear on your timeline.
You can change this under Settings & Account at any time.

No, thanks

Defence against disease

Immunology (Physical barrier and Innate immune system)
by

Sergi Fluvià Sabio

on 8 June 2013

Comments (0)

Please log in to add your comment.

Report abuse

Transcript of Defence against disease

DEFENCE
AGAINST
DISEASE Three lines of defence Intestine enzymes 2 3 1 Phsysical barrier Mechanisms Mucus Ciliated cells Vagina acid Lysozymes Intestine enzymes Skin Epithelial surface Types of response to the presence of a bacterial pathogen Secretion of antimicrobial peptides (defensins) Inflammation Activation of the complement system Defensins disrupt the membrane of the pathogen and kill the cell Isolation of the injured and stopping of the damage What is it? Plasma proteins. They form complexes to open pores in the pathogen, and consequently bacteria die. Caused for: Bacteria A bigger pathogen Macrophage recognise bacteria through receptors Salmonella typhimurium Mast cells are activated Two things happens Macropages phagocyte Secrete chemokines They secrete histamine What do the cytokines and histamine do? Dilate local blood vessels Increase the permeability More blood goes to the zone More fluid leaks to the tissue Secrete cytokines Monocytes Neutrophils Macrophages Ancylostoma duodenale Macrophages and neutrophils cannot engulf them Other method Macrophages Neutrophils Eosinophilis Physical barrier Innate immune system Adaptive immune system Lysosomal enzymes HNP3 dimer (α-defensin) HBD2 (β-defensin) Sergi Fluvià Sabio THANK YOU! http://arstechnica.com/science/2010/09/salmonella-causes-then-feeds-off-gut-inflammation/ Salmonella causes, then feeds off gut inflamation
Full transcript