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Toxicology For Dummies

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on 21 August 2014

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Transcript of Toxicology For Dummies

Toxicology For Dummies
Techniques
Significance
-Studies the adverse affects of drugs and toxins on people
-Concentration and dosage in relation to affects
Toxicologists are usually dealing with levels below original concentration of the toxins because the drug is dissipated and metabolized by the body
pH Testing
Acidic v Basic pH scale

Detect-Isolate-Analyze
Dissolve organic materials and control pH of solution.
Then using organic solvents extract using organic solvents
Screening and Confirmation
Screening Tests
Thin-layer chromatography(TLC)
Gas chromatography (GC)
Immunoassy

Checks likelihood of drug presence quickly
Confirm results of screening

Gas chromatography/mass spectrometry test

test gives unique spectra for types of toxins

Detection
drugs in bloodstream for 24 hours
detectable in urine for up to 72 hours
Hair
Blood is capillaries transports drugs
Grows at 1 cm/month
Only way to test for long term abuse
Other Toxins
Heavy Metals
Arsenic, Bismuth, Mercury, Thallium
Reinsch test-organs dissolved in HCl and copper strip inserted-dark coating indicates heavy metal
Carbon Monoxide
Blocks hemoglobin and causes asphyxiation
Spectrophotomrtric detection method
Gas chromatography test
Fatal concentration varies
Interpret how the drug influenced the behavior of the individual
Influence varies from person to person
Used to corroborate evidence found by other forensic departments
In death cases, toxicologists are called upon to verify presence or absence of drugs or toxins
Components of the Drug Recognition Process
The Breath Alcohol Test
Interview with arresting officer
Eye examination
Divided-Attention Psycho-physical tests
Vital signs examination
Dark room examinations
examination for Muscle rigidity
Examination for Injection sites
Suspects statements and other observations
Opinions of the evaluator
Toxicological examination
The 6 Categories
Drug Examination Process can suggest any of the following
Central Nervous System Depressants
Central Nervous System Stimulants
Hallucinogens
Dissociative Anesthetics
Inhalants
Narcotic Analgestics
Cannabis
Michael Jackson
Case Files
Found dead
Overdosed on sleep medication
What Is Toxicology?
Toxicology is the branch of forensic science that is concerned with detection, identification, and affects of substances in the body.
The Role of Toxicology in forensics
1970's LAPD developed a training program to educate police officers to recognize intoxicated states and which drugs the individual may be using
Drug Recognition Experts (DRE)
("Forensic Application of Gas Chromatography)
Works Cited
"Forensic Application of Gas Chromatography." Chromatography RSS. N.p., 24 Aug. 2007. Web. 29 Oct. 2013. <http://www.justchromatography.com/gc/forensic-gc>.

"Toxicology - What Is Toxicology?" News-Medical. N.p., n.d. Web. 29 Oct. 2013. <http://www.news-medical.net/health/Toxicology-What-is-Toxicology.aspx>.

"Toxicology: Understanding What the Michael Jackson Toxicology Report Is Looking At. « Crime and Forensic Blog | The National Museum of Crime and Punishment." Crime Museum. N.p., 4 Sept. 2009. Web. 29 Oct. 2013. <http://www.crimemuseum.org/blog/toxicology-understanding-what-the-michael-jackson-toxicology-report-is-looking-at/>.
(toxicology-What is toxicology?)
Mixing of multiple drugs in prescribed dosages can be fatal
Combining drugs can alter the affects and increase fatality rate
Michael Jackson's respiratory system was over-supresed
Austin, Ben, and Alex
(Toxicology: Understandin...)

Used to detect drugs and also explosion residue and ignitible fluids and fiber and blood samples
Full transcript