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Transcript of PABA
in our lives? - Found in natural food sources, like grains and foods of animal origin, which include: Grains Eggs Milk Meat Mushrooms Spinach Kidney Liver Molasses Molecular Structure: Physical Appearance: White or off-white crystalline powder Side Effects from Overdose Stability: Stable under normal conditions Chemical Properties of PABA Combustible; Sensitive to light & air - Incompatible with oxidizing agents Molar mass: 137.14 g/mol Density: 1.374 g/mL Melting point: Boiling point: 339.9°C (at 760mmHg) 186-189°C Solubility in water: 4.7 g/L (20°C) Flammability: - Can change in colour when exposed to light Extremely high doses (of over 8 grams)
can cause PABA toxicity Toxicity: Allergic Reactions - Oral and topical products that contain PABA can cause: skin rash, dizziness, fever and nausea - PABA is no longer used in most sunscreens due to risks Skin Damage and Skin Cancer - Its reflective properties causes searing of the skin - Applying PABA on skin creates more oxygenated free radicals and damages DNA (may cause skin cancer) Liver Damage - Daily doses of over 8 grams may lead to abnormalities or failure in liver functions Oral Overdose - Taking excess PABA orally can lead to coma or death Toxicity - Excess PABA is not excreted from body
- PABA would build up in body and can lead to toxicity - Sunscreen Rainbow Trout and Juvenile Fathead Minnows -Sunscreen: other UVA and UVB absorbers
-Vitiligo: topical corticosteroid therapy
-Infertility: clomiphene citrate, gonadotropins, metformin
-Dermatitis Herpetiformis: dapsone - Treating Vitiligo -Increase female fertility - Treating Anemia -Treating Dermatitis