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Gouty Arthritis

Anatomy & Phisiology Presentation
by

Isabel Nieto

on 18 April 2010

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Transcript of Gouty Arthritis

Double click anywhere & add an idea Gout is a disease that results from an overload of uric acid in the body. Individuals affected by gout suffer from an overload of uric acid that leads to the formation of tiny urate crystals that deposit in body tissues, especially in joints. The formation of crystals causes recurring attacks of joint inflammation or arthritis. Chronic gout can also lead to deposits of hard lumps of uric acid in and around joints. An abnormality in uric acid processing may cause:
Attacks of painful arthritis (gout attack)
Joint destruction
Kidney Stones
Decreased kidney function or even failure Gout has the unique distinction of being one of the most frequently recorded medical illnesses throughout history. This disease is often related to an inherited abnormality in the body's ability to process uric acid. Uric acid = End product of the breakdown of the purines we eat. Purines = Natural substances found in all of the body's cells, and in virtually all foods. Gouty arthritis is typically an extremely painful attack of rapid onset inflammation. Precipitated by deposits of uric acid crystals in the joint fluid (synovial fluid) and joint lining (synovial lining). Intense inflammation occurs when WBC's engulf the uric acid crystals and chemical messengers of inflammation are released causing pain, heat, and redness of the joint tissues. Approximately 5 million people in the United States suffer from gout. Did you know that none other than Benjamin Franklin suffered from terrible gouty arthritis? Men are nine times more likely to suffer from gout than women. Predominantly attacks males after puberty, with a peak age of 75. Women typically suffer from gout attacks after menopause. Symptoms of gout:

Rapid, intense onset of pain in the affected joint
Warmth
Swelling
Reddish Discoloration
Marked tenderness
Fever

Range of attacks can be hours or days; may subside with or without medication. In rare cases, an attack may last for weeks. Most individuals affected by gouty arthritis will experience repeated attacks over the years. ouch! Tenderness can be so intense, even the touch of a blanket over the affected joint can be unbearable. Synovial membrane = thin membrane in synovial (freely moving) joints. Lines the joint capsule and secretes synovial fluid. Tophus = nodular mass of uric acid crystals. There are over 100 Different kinds of arthritis; gout (a.k.a. gouty arthritis) is one of them. It is a common, complex form of arthritis, often affecting the joint at the base of the big toe. Gout can affect anyone... While gout usually affects the large joint of the big toe, it can occur in in other areas such as the ankles, knees, hands and wrists. The pain is likely most severe within the first 12 to 24 hours of the initial attack.
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