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Watson & Crick : DNA Structure
Transcript of Watson & Crick : DNA Structure
Structure of DNA
-Received a Ph.D in zoology
-Influenced by the geneticists H. J. Muller and T. M. Sonneborn, and by S. E. Luria
-Completed a thesis of the effects of X-rays on bacteriophage multiplication.
-Worked on bacterial virsues in Copenhagen
-Met Maurice Wilkens and saw the X-ray diffraction pattern of crystalline DNA; caused him to change his research to focus more on the chemistry of nucleic acids and proteins.
-B.S. in physics
-Worked as scientist for British Admiralty in WWII
-Joined Medical Research Council Unit until 1962 when the unit transfered into a larger building and became the Medical
-Research Council Laboratory of Molecular Biology
-Wrote thesis on x-ray diffraction: polypeptides and proteins.
Goal: To create a model of the DNA molecule
References from Rosalind Franklin's x-ray diffraction and helix
DNA is a 2 stranded double helix
One is moving in an upward direction
The other is moving in a downward direction
4 Nitrogenous bases
-Through their experiment, proof of DNA molecules being passed down from generation to generation is evident during the process of cell division.
- The two strands of DNA separate.
-On the two separate strands, a new strand bonds onto one of the two.
-This implies replication of the DNA, through the means of its structure.