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Cell Cycle Project
Transcript of Cell Cycle Project
Controlled by G1 GDK factors
Checkpont 2: Growth 2 to Mitotic Phase
DNA Replication- All replication complete
DNA damage/mutations cell size- Cant have
Cell size- Enough cellular organelles for both cells
Determined by S-phase CDKs, and Mitotic CDKs. Mitotic Phase
Checkpoint 3- M-Spindle Checkpoint
If the spindle fibers are attached to chromosomes.
Determined by: Mitotic CDKs DNA Replication is checked. Errors are corrected and cells double there organelles so that both daughter cells have the same amouint of chromosomes The chromatin condenses into chromosomes. The chromosome then copies itself so that each of the future cells can have the same set of DNA. They are known as sister chromatids. Prophase
In the nucleus the chromatin fibers become tightly coiled and the nucleoli disappear. Each duplicated chromosome appears as towo identical sister chromatids and the mitotic spindle begins to form. Pro-metaphase and Metaphase
During prometaphase the nuclear envelope fragments. The micro tubules of the spindle can now inevate the nucleus. Each of the two chromatids has a special structure called a kinetochore located at the centromere region. Some of the microtubules attach to the kinectochore which cause the chromosomes to begin to jerk. In metaphase the chromosomes line up and the centrosomes are at opposite polls. The centromeres all alighn and the chromosomes strattle the metaphase plate. The kinectochores of the sister chromatids attach to hte microtubules forming a spindle. Anaphase
The chromosomes begin to get pulled apart liberating the sister chromatids. They are pulled to together at there centriole away from each other. At the same time the poles of the cell move farther apart as the non kinectochore microtubules lengthen. Telephase
During telephase the nuclear envelop begins to reform. The chromatin fibers of each chromosome also become more coiiled. Mitosis which is the equal division of two identical cells is now complete. Division of two genetically identical cells. Division of the Cytoplasm Cytokinesis is the division of the cytoplasm. In animal cells a cleavagte furrow forms and in plant cells a cell wall forms making two identical daughter cells with two identical sets of DNA.