Loading presentation...

Present Remotely

Send the link below via email or IM

Copy

Present to your audience

Start remote presentation

  • Invited audience members will follow you as you navigate and present
  • People invited to a presentation do not need a Prezi account
  • This link expires 10 minutes after you close the presentation
  • A maximum of 30 users can follow your presentation
  • Learn more about this feature in our knowledge base article

Do you really want to delete this prezi?

Neither you, nor the coeditors you shared it with will be able to recover it again.

DeleteCancel

Make your likes visible on Facebook?

Connect your Facebook account to Prezi and let your likes appear on your timeline.
You can change this under Settings & Account at any time.

No, thanks

Intro to Pharmacology

No description
by

Jennifer Thankachan

on 11 November 2015

Comments (0)

Please log in to add your comment.

Report abuse

Transcript of Intro to Pharmacology

fundamentals of
nursing pharmacology

pharmacodynamics & pharmacokinetics
Professor Jennifer Thankachan, RN, MSN
Factors affecting absorption, distribution, metabolism & excretion
route of administration
amount of blood flow
form of the drug
solubility
protein binding
diseases
genetics
environment
age
Special considerations across the lifespan
developmental changes can affect drug metabolism...
Pharmacodynamics:
drug's action:
interaction between the drug and the body's cellular components

drug effect:
body's response from the action of the drug
agonist
intrinsic activity
antagonist
competitive vs. noncompetitive
nonselective
Pharmacokinetics:
kinetics

=

movement

pharmacokinetics
discusses how a drug is:
absorbed (taken into the body)
distributed (moved into various tissues)
metabolized (changed into a form that can be excreted)
excreted (removed from the body)
Pharmacokinetics
pharmacokinetics
also deals with:

1/2 life-
how long a drug stays in the body
onset of action
-
"how long 'til we see some action?"
peak

concentration level
-
absorption rate = elimination rate
duration of action
-
"how long will it last?"
Pediatric Considerations
infants have immature livers that metabolize drugs at a slower rate
decreased gastric acidity
weight-based dosing
pediatric patients are dependent
different epidemiology of pediatric disease processes
FDA
AAP
Considerations for the Elderly Patient
polypharmacy
diminished liver function (size, enzyme production)
decreased blood flow
decreased gastric acidity
What can the nurse do about it?
"what the body does to a drug"
FDA & other resources: patient education & health literacy
"what a drug does to the body"
absorption
distribution
metabolism/
excretion
Time-Response Curve
therapeutic index (margin of safety):
ratio of dose causing adverse effects vs. therapeutic dose
Pharmacodynamics:
Pharmacodynamics:
Full transcript