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Importance of Biochemistry in Pharmacy

Biology AP 12 Project
by

Kartiki Sharma

on 7 October 2014

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Transcript of Importance of Biochemistry in Pharmacy

Importance of Biochemistry in Pharmacy
Use of Biochemistry
Gives an idea of drugs' constitution

Its change of degradation with varying temperature

Their metabolism by biochemical reactions (in presence of enzymes & other substances)
Tylenol
generic name: acetaminophen/ paracetamol
Metabolism of Acetaminophen
Role of a Pharmacist
Detection /Preventions of ADRs (Adverse drug reaction)
Cont'd
1. Mechanism of action: inhibits
COX

in the body blocks synthesis of
prostaglandins
involved in pain pathways

By: Priyanka Prince &
Kartiki Sharma
What is
Biochemistry?
Chemistry ( or chemical activity) of living things
Living things
Chemical reactions
Checking for contraindications
Choice and monitoring of therapy
Know which parameters may be affected by drugs
Must understand common biochemical tests
Example
molecular formula:C H NO
8
9
2
structural formula:
relieves pain and decreases fever
3. max dose: 4g/day
overdose
hepatotoxicity
occurs when
large amount
of alcohol (which is also metabolized in liver) is consumed

liver enzyme
CYP2E1
are enhanced and the pathway to toxic product is followed (more often)

higher risk of toxicity
and liver damage,
hepatotoxicity
BIOCHEMISTRY
DESCRIBES
ORIGIN
FORMATION
DEFICIENCY
SYMPTOMS
FUNCTION
ENZYMES, CARBOHYDRATES, PROTEINS, DNA, RNA, etc.
Cont'd
Other Effects on Metabolism
Addition of alcohol
AWWWW!!!!!
lmao you are really high
U ALREADY ACE EVERYTHING!!
no not really... :( there is always room for improvement and sometimes I just wish I was someone else like my sis or something... DX
EXTRA MUCH
so you'll be reading 1, 2, 3 slides
SURE
:( I really mean it... I wonder if everyone feels like that. wanting to be someone else
I DON'T
dunno but I just don't feel like myself ever since grade 7... lots happened
so back on to the presentation?
MYSTERIOUS......SURE
lol so are you good with 1-5 slides?
U SAID 1-3
BUT OK
5th one is the role of pharmacist
If you want something else from later parts I can switch with you; whatever you feel like.
NO IT'S FINE
alrighty... so i'll do from 6-11
YAY!!
9 is the video
would you like to do the conclusion??? >:D
OF COURSE
NOT
that I still have to write
omg such a troll O_O
LET'S DO THE CONCLUSION TOGETHR
ok
let's make a new slide
circle or square?
YAY!!
yay isn't an option
CIRCLE
oh k

In Conclusion...
Biochemistry is essential for studies in pharmacy, because:
reveals the
drug's metabolism,

effectiveness
and
interaction of a drug
with the human body
educates them on ADRs and dangers of the drug
and the areas of the body that are exposed to risks
improve the performance of medicine in the future
Sulfates
Glucoronidation
excretion from the kidney
Non-toxic
Non-toxic
Toxic
Non-toxic
Citations:
Peasley, M. (2014, September 7). Biochemistry & biochemical tests for the pharmacist. prezi.com. Retrieved September 27, 2014, from http://prezi.com/m0g27zpdgid9/biochemistry-biochemical-tests-for-the-pharmacist/
What Is The Importance Of Biochemistry?. (n.d.). - Blurtit. Retrieved September 27, 2014, from http://science.blurtit.com/289418/what-is-the-importance-of-biochemistry
Tylenol (Acetaminophen) Drug Information: Description, User Reviews, Drug Side Effects, Interactions - Prescribing Information at RxList. (2007, November 7). RxList. Retrieved September 30, 2014, from http://www.rxlist.com/tylenol-drug.htm


Ask The Professor. (n.d.). How does acetaminophen relieve pain?. Retrieved October 2, 2014, from http://tuftsjournal.tufts.edu/2008/04/professor/01/
Adesina, D. A. (2013, September 4). Acetaminophen (Tylenol) Metabolism and Toxicity. YouTube. Retrieved October 2, 2014.
*
* website link unable to cite due to a problem with prezi
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