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Oxygenated v.s Deoxygenated Hemoglobin

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by

Tiarra Fisher

on 2 June 2014

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Transcript of Oxygenated v.s Deoxygenated Hemoglobin

Oxygenated
Formed through the transportation of oxygen to cells in tissues
Oxygen binds with the heme protein in hemoglobin
Taut (tense) and R (relaxed) are two states of hemoglobin at which deciding factors allow oxygen to either bind easier or release
Deoxygenated
Is not bounded to oxygen
Has a higher absorption spectra (radiation) of 940 nm
The 940 nm cause the blue/purple color when the body does not have a sufficient amount of oxygen supply
Oxygenated v.s Deoxygenated Hemoglobin
Protein Function,Myoglobin and Hemoglobin
The Bohr effect relates to the association and disassociation because, Christian Bohr, a scientist uncovered the factors that allows hemoglobin to release and bind oxygen. (tense and relaxed states of hemoglobin). One of the main factors he uncovered was PH, he found that a lower PH causes the releasing of oxygen inhemoglobin while a higher PH causes the binding of oxygen to hemoglobin proteins in red blood cells.
The Bohr effect for the association and disassociation of oxygen and hemoglobin
Sickle cell anemia
Molecular difference between normal and sickle cell forms of hemoglobin
Difference between normal and sickle red blood cells
Sickle cells have a crescent moon shape caused by the mutation in the protein make up. They differ from normal red blood cells because they crescent moon shape is not able to carry oxygen well causeing anyone with sickle cell anemia to be in constant pain because of lack of oxygen being delivered to their tissues.
Diseased cells v.s Normal
https://www.google.com/search?q=diagram+of+the+amino+acid+difference+in+sickle+cell+anemia&source=lnms&tbm=isch&sa=X&ei=7X-LU53WJtLmsATJ64CQBg&ved=0CAYQ_AUoAQ&biw=1366&bih=624&dpr=1#facrc=_&imgdii=_&imgrc=y3s0dSXSjw5U0M%253A%3BqOkwMHQP3lUzgM%3Bhttp%253A%252F%252Fbiochemmarie.files.wordpress.com%252F2013%252F04%252F437300.gif%3Bhttp%253A%252F%252Fbiochemmarie.wordpress.com%252Fpage%252F3%252F%3B316%3B193
https://www.google.com/search?q=diagram+of+the+amino+acid+difference+in+sickle+cell+anemia&source=lnms&tbm=isch&sa=X&ei=7X-LU53WJtLmsATJ64CQBg&ved=0CAYQ_AUoAQ&biw=1366&bih=624&dpr=1#q=diagram+of+difference+between+normal+and+sickle+red+blood+cells&tbm=isch&facrc=_&imgdii=_&imgrc=uBor3ieZjR44QM%253A%3BaWkRs-lKvectdM%3Bhttp%253A%252F%252Fwww.mudphudder.com%252Fwp-content%252Fuploads%252F2008%252F11%252Fnormal-and-sickle-cell-rbc-sem.jpg%3Bhttp%253A%252F%252Fejgorgas.edublogs.org%252F%3B1131%3B525
Sickle cell is inherited from parents to the child the same hair or eye color is passed down. for example from
(http://www.stjude.org/stjude/v/index.jsp?vgnextoid=9454db6324d6f110VgnVCM1000001e0215acRCRD)
a one parent with a sickle cell trait has a 50% chance of passing is down to their children while two parents with the sickle cell trait have a 25% chance of passing it to the children.
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