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Transcript of Hemophilia
Pregnant women who are known hemophilia carriers can have their unborn babies diagnosed with the disorder as early as 10 weeks into their pregnancies. Women can also have "preimplantation diagnosis." For this process, women have their eggs removed and fertilized by sperm in a laboratory. The embryos are then tested for hemophilia. Only embryos without the disorder are implanted in the womb. Introduction: Hemophilia Hemophilia is a bleeding disorder that slows the blood clotting process. People with this condition experience prolonged bleeding after being injured or a surgery and can bleed externally as well as internally.
The two types of this condition are:
also known as classic hemophilia or F8 deficiency
also known as Christmas disease or F9 deficiency Symptoms: The main symptom is bleeding of any age, sex, or progression of the disease. Children who have hemophilia may not have signs unless they have excessive bleeding from a surgery. Bleeding can occur in the joints and in the brain. If in joints, bleeding causes tightness in joint with no real pain or any visible signs of bleeding. The joint then becomes swollen, hot to touch, and painful to bend. Overtime, swelling and bleeding continue and eventually movement in joint is temporarily lost and can cause damage. Inheritance: It is a genetic disease that causes mutations in the genes F8, which is responsible for hemophilia A, or in the F9 gene which causes hemophilia B. They are proteins that work together in the blood clotting process. Hemophilia A and hemophilia B are inherited in an X-linked recessive trait, so it is located on the X chromosome. It is more common in males than in females. Signs: Signs of external bleeding may include:
Bleeding from mouth or nose for no obvious reason
Heavy and/or continuous bleeding from a minor cut
Signs of internal bleeding may include:
Blood in the urine (from bleeding in the kidneys or bladder)
Blood in the stool (from bleeding in the intestines or stomach)
Large bruises (from bleeding into the large muscles of the body)
Signs of bleeding in the brain include:
Long-lasting, painful headaches or neck pain/stiffness
Sleepiness or changes in behavior
Sudden weakness or clumsiness of the arms or legs or problems walking
Double vision, convulsions, or seizures Cure/Treatment: The bleeding problems of hemophilia A and hemophilia B are the same but knowing which type is important because the treatments are different. Like Desmopressin is a man-made hormone used to treat people who have mild to moderate hemophilia A only and it usually is given by injection or as nasal spray.
The main treatment for hemophilia is called replacement therapy. Concentrates of clotting F8 or F9 are slowly dripped or injected into a vein. A hemophiliac person can also take recombinant clotting factors. Antifibrinolytic medicines is taken with replacement therapy and are usually given as a pill, and they help keep blood clots from breaking down.
Preventive or prophylactic therapy (regular basis)
Demand therapy (as-needed basis)
Home treatment is helpful just for day-to-day care. A cold pack helps with bumps and bruises and popsicles help with bleeding in mouth. Basic child proofing is in order for a hemophiliac child/toddler. Most sports are now limited to a few like swimming, biking and golf.
Aspirin, ibuprofen, and naproxen, football, hockey, and wrestling are NOT safe medication to take and sports to play for hemophiliac people. Works Cited "Heal your headache with yoga." http://www.womenshealthmag.com/yoga/yoga-to-soothe-headaches. 2013. (February 20, 2013).
"Hemophilia." <http://bryanking.net/tag/hemophilia/>. (February 20, 2013).
“Hemophilia.” <http://ghr.nlm.nih.gov/condition/hemophilia>. Genetics Home Reference. 1993. (February 16, 2013).
“Hemophilia.” <http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001564/>. National Center for Biotechnology Information. 2012. (February 13, 2013).
“Hemophilia.” <http://www.nhlbi.nih.gov/health/health-topics/topics/hemophilia>. National Heart, Lung, and Blood Institute. 2011. (February 13, 2013).
"Inheritance of Hemophilia." <http://www.ihtc.org/medical-professionals/blood-disorders/bleeding-disorders/hemophilia-a-and-b/>. 2011. (February 20, 2013.)
Laura. "Who Discovered Hemophilia?" <http://www.everydayguide.com/who-discovered-hemophilia/>. 2013. (February 20, 2013).
"Red, White, & You." <http://www.hemophilia.ca/en/about-the-chs/to-support-us/red-white---you/>. 2013 (February 21, 2013)