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LSD Presentation

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Social Psychology Group

on 4 June 2016

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Transcript of LSD Presentation

LSD
LSD Group Presentation
Hippies
By Daniela Gonzalez,
Angie Mejia-Arias, and
Michelle Hodgson-Smith

Albert Hoffman
Timothy Leary
fin.
Lysergic acid diethylamide
LSD
Where does it come from?
- the ergot alkaloids is cultured
­ the ergot alkaloid is synthesized into a lysergic acid compound called iso-lysergic acid hydrazide chemicals added and then heated
- then it's isomerized
- then it is cooled
- mixed with acid and base
- evaporated
- produce active LSD
- LSD is then purified and crystallized
How is it used?
References
Dependence
Prevention
Abuse
Levinthal, C. F., (2012). Drugs, Behavior, and Modern
Society (7th Edition). Boston: Allyn & Bacon.
*Research chemist, Sandoz Pharmaceuticals
Basel, Switzerland
*Discovered effects of LSD April, 1943 - he was
working on a drug to help with childbirth
*First dose absorbed through fingertips
*First deliberate dose=.25 mg (5x "hit" today)
*Sandoz applied for FDA approval in 1953
as possible schizophrenia medication
*Sent samples to laboratories for study
The first man to experience an acid trip
Ways of administration:

- blotter LSD, left under the tongue for 15-20 minutes or swallowed
- liquid LSD is dropped under tongue or mixed with water
- sugar cubes that can be eaten
- dropping it into the eye
- can also be taken intravenously (uncommon)
- dipping thumb into liquid or crystal LSD
Physical Effects
*Pupil dilation - the first sign
*Digestive tract - becomes
effected causing diarrhea
*Nausea - can be present as
long as the trip lasts
*Alert/active - most people
are active until the effects
have worn off
*Body temp - temp may lower
or fever and chills may
overcome the person
Psychological Effects
LSD is considered, among others, the
most hallucinogenic drug. Hallucinations
take place in our senses, mostly visual, but
no limit to other senses
*Anxiety
*HDDP - flashbacks
*Depression
*Suicidal thoughts
*Impairments of mental function
The BAD Trip
There have been bad trips associated with LSD; including icon, Boy George, who wrote in an autobiography about an experience he had at a club. He described, "everything was breathing and coming at me. I started shrinking and felt scared."
People have testified seeing snakes and bugs after injecting 125 micrograms of LSD.
Others have reported experiencing Post Traumatic Stress, being hostile, destructive, and violent
*LSD studies are
now being conducted
for possible use
in treatment of
alcoholism*
"Mr. LSD"
*Clinical psychologist/lecturer,
Harvard University
*Psilocybin was his "gateway drug" - 1960
it was his "...deepest religous experience..."
*Like LSD, Psilocybin stimulates serotonin
*Conducted "studies" on Psilocybin @ Harvard
*In 1961, began LSD studies outside Harvard
*Published writings sparked Harvard
investigation
*Fired from Harvard, created media craze,
first Harvard faculty member fired in the
20th century
*LSD now a household name
Youth in revolt - 1960s
*against the conformity of the 50s, the war
and "the man"
*used drugs as a way to rebel & to expand the mind
*LSD was a drug of use and also a symbol of
their cause and era
*there were psychedelic churches, festivals,
light shows, etc.
*enclaves in most decent sized cities
*drug culture tours
High School LSD Users
Changes from 2007 to 2008
*increase in past month usage among 12th graders
*decrease in perceived risk among 12th graders
2008 Monitoring the Future Survey
8th graders 10th graders 12th graders

Lifetime 1.9% 2.6% 4%

Past Year 1.3% 1.8% 2.7%

Past Month 0.5% 0.7% 1.1%
2007 National Survey on Drug Use and Health
* more than 22.7 million people 12+ years reported using LSD in their lifetime
*fewer than 620k of them had reported using LSD in past year
"...turn on to the scene,
tune in to what's happening,
drop out...
and follow me"
-Timothy Leary
Unlikely for 3 Reasons
*tolerance - hallucinogens produce
tolerance effects faster than any
other type of drug
* not an easy high - draining and
exhausting, lasts for hours
*unpredictable/unreliable
Effective Dose
*as low as 10 mcg
*average dose - 50 to 150 mcg
*by comparison - 325k mcg/aspirin
Lethal Dose
*LD=roughly 300-600x ED
or 3,000-90,000 mcg
15,000 mcg = possibly lethal
or @ the very least, really f*@#ing high!!
Treatment
*as with other drugs, education is very
important in preventing LSD abuse
*promoting parental involvement and
increasing protective factors
also useful
*since dependence is unlikely, treatment
is usually unnecessary
*if treatment is necessary, a traditional
in/out-patient program with individual
and/or group counseling can be used
*treatment for adverse psychological
effects such as anxiety, depression,
and flashbacks can be done by a
psychologist or therapist
POP CULTURE
Lucy in the Sky with Diamonds
Krebs, T., & Johansen, P. (2012). Lysergic acid diethylamide (LSD) for
alchoholism: meta-analysis of randomized control trials. Journal of
Psychopharmacology, 26(7), 944-1002. doi:10.1177/029881112439253
National Institute on Drug Abuse. (2009). Monitoring the future
survey, national survey on drug use and health. Drug
Facts: Hallucinogens. Retrieved from www.drugabuse.org
Timeline
1938 - first synthesized
1943 - compounded for medical use
1949 - first brought to US
1950 - first paper written about LSD
America Psychiatric Journal
1959 - international conference
1966 - made illegal in US
Salt Lake County 12th graders 2011
*10% had used hallucinogen
in lifetime
*4% had used hallucinogen
in past month
Europeans Aged 15 - 24
*4.2% have taken LSD in lifetime
*Past year usage exceeded 1% in Bulgaria,
Czech Republic, Latvia, Estonia, Italy,
Hungary, and Poland
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