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Acquisition and Pathology of Bacterial Diseases
Transcript of Acquisition and Pathology of Bacterial Diseases
Acquisition and Pathogenicity of Bacterial Diseases
What methods, if any, are used to block transmission of this pathogen?
Doxycycline, an antibiotic, is usually started in the first 5 days. Treatment should always begin before laboratory results return or symptoms of severe disease, develop.
How likely is it that the host will acquire a disease following exposure to a pathogen
The pathogen typically takes 10 to 20 hours of feeding to transfer enough to cause an infection. Although not all ticks carry pathogens, it should be assumed that it does and should be removed from the body immediately using tweezers.
The pathogen causes a serious illness that can be fatal in the first eight days of symptoms if not treated correctly. Once the host gets a fever, it leads to other symptoms such as:
• a rash 2 to 5 days after a fever
• headache •abdominal pain
•nausea, • lack of appetite
How does the pathogen damage the host?
Rocky Mountain Spotted Fever CDC -http://www.cdc.gov/rmsf/
Medical Microbiology Fall 2000- http://www.atsu.edu/faculty/chamberlain/website/lects/rickett.htm
Fatal Human Infection with Rickettsia rickettsii CDC - http://wwwnc.cdc.gov/eid/article/12/4/05-1282_article.htm
Habitat- Inside the Host Cell - http://bioweb.uwlax.edu/bio203/s2008/gibson_chel/Habitat.htm
What is the source of the infectious disease you are researching?
Rickettsia rickettsii is a bacterium that causes the disease "Rocky Mountain Spotted Fever." The bacterium is spread from certain infected ticks. These include the American dog tick , Rocky Mountain wood tick, and brown dog tick
How does the pathogen exit the host?
How is the pathogen transferred from one environment to another?
During the tick's meal, a small amount of saliva transfers to the tick's host. The pathogen is transferred through this saliva. The pathogen is not spread from person to person.
How does the pathogen enter
the host ?
What structures does the
pathogen use for attachment?
Which cells of the host does the pathogen attach to?
The pathogen is spread to ticks when ticks feed on a previously infected animal. The pathogen lives inside the tick asymptotically. The pathogen then infects animals that the tick feeds on.
Prevention of tick bites is the main method used to prevent transmission. Since ticks also spread other pathogens, it is highly recommended to take actions against ticks when in a vulnerable area. These actions include using tick repellants and avoiding wooded areas
The pathogen enters the host tick when the tick feeds on the blood of an infected animal. The pathogen spreads to the tick which then carries it to different environments
Rickettsia rickettsii enters the skin and spreads through the blood stream to infect the brain, lungs, heart,kidneys, liver and other organs. It affects the smooth muscle cells of small blood cells. The Rickettsia rickettsii also attaches to the endothelial cell membrane using phagocytosis. Then, the Rickettsia escapes from the phagosome before it joins with the lysosome.
A Rocky Mountain Wood tick
Removal of a tick
Early stage rash