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Penicillins

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by

islam talaat

on 10 October 2012

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Transcript of Penicillins

The first discovered Antibiotic Penicillin Stucture Defenition Mechanism of action Indications Penicillin gets widely distributed through out the body and reaches high concentration in the urine. It also reaches significant level in bile, liver, skeletal muscle, brain and plasma. Its level gets raised in the presence of inflammation . Pharmacokinetics Penicillins are contraindicated in patients with a history
of hypersensitivity to penicillin or the cephalosporins . Contraindications Side effects Birth control pills (Gynera)
Anti coagulants (Aspirin)
Beta adrenergic blocker (Inderal)
Celebrex (celecoxib)
Claritin (loratadine)
Flagyl (metronidazole)
Lexapro (escitalopram)
Lyrica (pregabalin)
Neurontin (gabapentin)
Nexium (esomeprazole)
Paracetamol (acetaminophen)
Prozac (fluoxetine)
Seroquel (quetiapine)
Singulair (montelukast)
Synthroid (levothyroxine)
Tylenol (acetaminophen)
Vicodin (acetaminophen/hydrocodone)
Xanax (alprazolam)
Zoloft (sertraline) Interactions Case study penicillin is a β-lactam antibiotic , derived from penicillium fungi . penicillin is related to a group of antibiotics called "Inhibitors of cell wall synthesis" .
This type of antibiotics act as follows : Classification Penicillins Extended Spectrum
Penicillins Natural
Penicillins Penicillinase-Resistant
Penicillins Aminopenicillins Use of
Penicillins Infectious
Disease Prophylaxis Hypersensitivity
Reactions Candidiasis
or
Moniliasis Other side effects such as
thrombocytopenia ... leukopenia ... glossitis ... stomatitis ... phlebitis superinfection these drugs must be checked in combination with penicillin : 1. When reviewing Ms. Robertson’s culture and sensitivity test results, the nurse learns that the bacteria causing Ms. Robertson’s infection are sensitive to penicillin.
The nurse interprets this result to mean that :
A. Ms. Robertson is allergic to penicillin
B. penicillin will be effective in treating the infection
C. penicillin will not be effective in treating the
infection
D. the test must be repeated to obtain accurate results 2. Mr. Thomas, who is receiving oral penicillin, reports he has a sore mouth. Upon inspection the nurse notes a black, furry tongue and bright red oral mucous membranes.
The primary care provider is notified immediately because these symptoms may be caused by :
A. a vitamin C deficiency
B. a superinfection
C. dehydration
D. poor oral hygiene 3. The nurse correctly administers penicillin V .
A. 1 hour before or 2 hours after meals
B. without regard to meals
C. with meals to prevent gastrointestinal upset
D. every 3 hours around the clock 4. After administering penicillin in an outpatient setting
the nurse .
A. asks the patient to wait 10 to 15 minutes before
leaving the clinic
B. instructs the patient to report any numbness or
tingling of the extremities
C. keeps pressure on the injection site for 10 minutes
D. asks the patient to wait in the area for at least
30 minutes
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