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Hepatitis B

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arabel hector

on 9 December 2014

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Transcript of Hepatitis B

Hepatitis B
About Hep. B
What is Hepatitis B?
Hepatitis B is a serious liver infection caused by the Hepatitis B virus (HBV).
What does HBV do to the human body?
It causes inflammation of the liver, which can lead to cirrhosis, liver cancer, or liver failure.
About the Hepatitis B Virus
How do you get Hepatitis B?
Sexual contact:
unprotected sex with an infected partner whose blood, saliva, semen or vaginal secretions enter your body.
Sharing needles
with an infected individual or
accidental needle sticks
(for health care workers).
Mother to child:
Pregnant women infected with HBV can pass the virus to their babies during childbirth. However, the newborn can be vaccinated to avoid getting infected.
In Conclusion...
How HBV affects the body
Different Types of Hep. B
Acute HBV
Acute hepatitis B infection lasts less than six months. Most healthy adults (90%) who are infected with the Hepatitis B virus will recover and develop protective antibodies against future Hepatitis B infections.
Chronic HBV
Chronic Hep. B lasts longer than 6 months, and it is with this type of infection that can lead to liver problems. 90% of infants and up to 50% of young children infected with Hepatitis B will not get rid of the virus and will develop a chronic infection.
Symptoms from Hep. B
Fever
Joint pain
Dark urine
Abdominal pain
Loss of appetite
Nausea and vomiting
Weakness and fatigue
Bloated or swollen stomach
Jaundice - Yellowing of the skin & the sclera of the eye
The Liver
Resources
The Hepatitis Virus Database:
http://www.ibibiobase.com/projects/hepatitis/hepatitis-aB.htm
1998-2014 Mayo Foundation for Medical Education and Research:
http://www.mayoclinic.org/diseases-conditions/hepatitis-b/basics/definition/con-20022210
WebMD Medical Reference from Healthwise:
http://www.webmd.com/hepatitis/hepb-guide/hepatitis-b-topic-overview#
If cirrhosis becomes very severe, liver failure can occur. This means the liver is unable to filter wastes, toxins, and drugs from the blood. It can no longer produce clotting factors needed to stop bleeding. Liver failure can lead to DEATH
What can Hep. B do to my liver?
The virus is passed from person to person through blood, semen or other body fluids.
A simple blood test can tell if you've been infected or not
1. HBV vaccine! (Recombivax HB and Engerix-B)
Hepatitis B infection does not usually require treatment
because most adults clear the infection spontaneously. That is,
if you have Acute Hepatitis B
.
The hepatitis B virus is classified as the type species of the
Orthohepadnavirus
, which contains three other species: the Ground squirrel hepatitis virus, Woodchuck hepatitis virus, and the Woolly monkey hepatitis B virus. Hepatitis B virus is a member of the
Hepadnavirus family
.
The virus particle (virion) consists of an outer lipid envelope and an icosahedral nucleocapsid core composed of protein. The nucleocapsid encloses the viral DNA and a DNA polymerase that has reverse transcriptase activity similar to retroviruses. The outer envelope contains embedded proteins which are involved in viral binding of, and entry into, susceptible cells. The virus is one of the smallest enveloped animal viruses with a virion diameter of 42 nm
Prevention & Treatment
What to do if you become infected
If you haven't been vaccinated or aren't sure whether you've been vaccinated or whether you responded to the vaccination, receiving an
injection of hepatitis B immune globulin

within 12 hours
of coming in contact with the virus may help protect you from developing hepatitis B.
You should be vaccinated at the same time
.
Treatment
Antiviral medications

1.
Lamivudine (Epivir)
: - inhibits hepatitis B viral DNA synthesis.

2.
Adefovir dipivoxil (Hepsera)
: inhibits DNA polymerase activity and reverse transcriptase.

3.
Entecavir (Baraclude)
: It works by inhibiting the function of Hepatitis B virus.

4. Telbivudine (Tyzeka)

What are your options
if you have Chronic Hep. B
?
Simple Steps to Prevent and Take Action
This synthetic version of a substance (produced by the body to fight infection) is used mainly for young people with Hepatitis B who don't want to undergo long-term treatment or who might want to get pregnant within a few years. It's given by injection. Side effects may include depression, difficulty breathing and chest tightness.
Interferon Alfa-2b (
Intron A
)
Liver Transplant
If your liver has been severely damaged, a liver transplant may be an option. During a liver transplant, the surgeon removes your damaged liver and replaces it with a healthy liver. Most transplanted livers come from deceased donors, though a small number come from living donors who donate a portion of their livers.
Hep. B virus is a serious life threatening microorganism. It infects the liver, which helps with filtering toxins in your body. Your liver depends on you to take care of so it can take care of you. It needs your help every day to keep it healthy and hepatitis free. So keep it clean!
Also, don’t share items that may have been contaminated with someone else’s blood, such as toothbrushes, razors and needles used for body piercing, tattooing or acupuncture.
Group 10:
Wilna Petit
Marie Debuisson
Kerps Charles
Arabel Hector,
Sandra Baptiste
MCB 2010
Mon. 5:40p
Prof. Bartra-Schesser
Full transcript