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Lysosomes and Peroxisomes

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Matthew Seigel

on 8 December 2014

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Transcript of Lysosomes and Peroxisomes

Interaction with other organelles
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Interaction with other organelles
Specific Function and creation
Lysosomes and Peroxisomes
Christian de Duve
Christian de Duve and his colleges discovered the lysosome in the 1950's. When they were examining a liver cell for the metabolism of carbohydrates he switched his approach to cell fractionation. He then discovered the enzyme acid phosphate that lead him to discover the lysosome with an electron microscopy. In 1974 he won the Nobel Prize in Physiology or medicine much of his consideration was for his work with lysosome. This discovery helped explain what happen to damaged cell organelles.
Lysosomes are membrane bond organelles that are free floating in the cell cytoplasm. Lysosomes are found in every animal eukaryotic cell.
Location of Lysosomes
The function of a lysosome organelles is to digest food, bacteria, and break down damaged organelles. Lysosomes are created by the Golgi apparatus. The enzymes however are created in the rough endoplasmic reticulum. Theses enzymes then go to the Golgi apparatus where a small vesicle is pinched off and the lysosome is created.
Source: biology4kids.com
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Specific Function and creation
The way that lysosomes interact with other organelles is crucial to the cell existance. Since lysosomes play a role in the digestion for the cell. Part of its function is breaking down food vacuoles. Lysosomes will attach to the food vacuole and release their enzymes into the vacuole. The enzymes will then digest the food and release the nutrients into the cell.
Source: www.nndb.com
Food Vacuole Interaction
Interaction with Organelles
Lysosomes will also do this for damaged organelles. However, they will take a different approach by engulfing the damaged organelle. The contents of the damaged organelle are then dismantled and its molecules are available for reuse.
Fun Facts
Lysosomes help the liver to recycle half of its macromolecules every week.
Abnormal Lysosomes can cause fatal diseases
Scientist are still trying to figure out why the enzymes that are in the lysosome don't break the lysosome membrane.
Peroxisomes like lysosomes are located in the cytoplasm of the cell. Peroxisomes also have a membrane holding their enzymes. However, peroxisomes are different from lysosomes because peroxisomes are in both plant and animal cells. Also, peroxisomes have oxidative enzymes which are different from lysosomes.
Peroxisomes have enzymes which need oxygen to operate. These enzymes specialize is breakdown of fatty acids but also help digest alcohol and amino acids too. Not only this but they help create cholesterol and purines such as adenine and guanine.
Dr. Johannes Rhodin is the first scientist to look at and describe a peroxisome molecule. However, Christian de Duve was the one who first identified peroxisomes as organelles. This was determined using Dr. Rhodin's notes.
Peroxisomes have a very important byproduct in hydrogen peroxide (H2O2). After these enzymes finish their duty, they take in the hydrogen peroxide and are able to break it down again into water and oxygen.
Peroxisomes are created from different peroxisomal matrix proteins that re arranged in a specific order and are assembled in the rough endoplasmic reticulum.
Peroxisomes play a major role in cell digestion. It helps largely with the digestion of ethanol. For that reason the liver will have more peroxisomes than most other cells. Peroxisomes interact with the mitochondria oxidation of fatty acids and the metabolism of reactive oxygen species. It is also in close contact with the endoplasmic reticulum and share several enzymes.
Fun Facts
The membrane of the peroxisomes may come from the endoplasmic reticulum scientist are still researching.
Peroxisomes continue to grow in size till they split into two.
Biology Concepts & Connections 5th Edition
By Neil A. Reece, Jane B, Taylor, Martha R. Simon, Eric J. Campbell
When a lysosome attaches to or engulfs a molecule/organelle what happens to the nutrition's that were digested?
what is something lysosomes and peroxisomes have in common?
When lysosomes dismantle a damaged organelle the broken down molecules can then be......
Peroxisomes have what type of enzyme?
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