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Biotechnology Timeline (1950s-2010s)

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Makenzie Doherty

on 13 January 2015

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Transcript of Biotechnology Timeline (1950s-2010s)

Biotechnology Timeline (1950s-2010s)
Transfer of marrow into irradiated mice shows that marrow, life spleen, is regenerative.
Egon Lorenz created an experiment to test whether marrow could regenerate in the blood system.
This experiment sets the foundation for bone marrow transplants.
French scientists discover mRNA.
Scientists understand genetic code for the first time.
The U.S. National Institutes of Health forms a recombinant DNA Advisory Committee. The Committee oversaw recombinant genetic research.
In Japan the first vaccine for the chicken pox was developed.
DNA ligase, which links DNA fragments together, is used for the first time.
The DNA composition of humans is discovered to be 99 percent similar to that of chimpanzees and gorillas.
The purified enzyme reverse transcriptase is first used to synthesize complementary DNA from purified messenger RNA in a test tube.
First application of gene therapy in human patients.
Martin Cline does this after doing experiments on mouse blood marrow.
very controversial.
Congress begins to fund the Human Genome Project, which is an attempt at mapping and sequencing the human genetic code.
Dr. Arthur Kornberg of Washington University in St. Louis makes DNA in a test tube for the first time. The first automatic protein sequencer, the Moore-Stein amino acid analyzer, is developed.
Human Genome Project is formally launched.
Initiated by the US Department of Energy.
Started to determine the sequence of chemical base pairs which make up DNA, and to identify and map all the genes in the human genome.
First separation of cancer stem cells from the majority of cells in a cancer
Science and Nature magazines publish the human genome sequence, making it possible for scientists all over the world to begin researching new treatments for diseases that have genetic origins, such as cancer, heart disease, Parkinson's and Alzheimer's.
Chemists in Japan make the first artificial DNA molecule.
The human genome is able to be sequenced for 2,000 dollars in less than one week.
The FDA approves the first cord blood therapy to be used in hematopoietic stem cell transplants.
FDA approves the first genetic based medicine for osteoporosis.
Harvard researchers created the "Lung on a Chip"
Independent groups from USA, China, and Germany synthesize insulin.
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