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Nicotine:

Alpha-7 Nicotinic receptor: a7nAChR

(type of nicotinic acetylcholine receptor)

References:

What is Chemogenetics?

The process by which macromolecules can be engineered to interact with previously unrecognizable smaller molecules.

1. Varenicline. En.wikipedia.org. https://en.wikipedia.org/wiki/Varenicline. Published 2019. Accessed May 14, 2019.

2. Chemogenetics. En.wikipedia.org. https://en.wikipedia.org/wiki/Chemogenetics. Published 2019. Accessed May 14, 2019.

3. Alpha-7 nicotinic receptor. En.wikipedia.org. https://en.wikipedia.org/wiki/Alpha-7_nicotinic_receptor#Agonists. Published 2019. Accessed May 14, 2019.

  • Formula: C10H14N2
  • Molar mass: 162.23 g/mol
  • Boiling point: 247 °C
  • Density: 1.01 g/cm³
  • Density: 1.01

Drug name: Varenicline

Trade names: Champix, Chantix

  • Molar mass: 211.267 g/mol
  • Formula: C13H13N3
  • Metabolism: Limited (<10%)

Varenicline is a prescription medication used to treat nicotine addiction. It reduces both craving for and decreases pleasurable effects of cigarettes and other tobacco based products.

The Chemogenetics Method

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