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"Out damned spot, out, I say!" (Act 5. scene 1. 37).
"Whence is that knocking? How is 't with me when every noise appalls me? What hands are here! Ha, they pluck out mine eyes. Will all great Neptune's ocean wash this blood clean from my hand? No, this my hand will rather the multitudinous seas incarnadine, making the green one red" (Act 2 scene2 74-81).
"What man dare, I dare. Approach thou like the rugged Russian bear, the armed rhinoceros, or th' Hyrcan tiger; take any shape but that, and firm nerves shall never tremble" (Act 3. scene 4 121-125).
Macbeth murdering Duncan for his ambition causes him and Lady Macbeth to become paranoid to everything around them due to their guilt. This eventually results in the deaths of Macbeth and Lady Macbeth.
"Still it cried 'Sleep no more!' to all the house. 'Glamis hath murdered sleep, and therefore Cawdor shall sleep no more. Macbeth shall sleep no more'"(Act 2. scene 2. 54-57).