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Quadrupedal

Bipedal

Quadrupedal

Most Common

Osteoarthritis is the most common joint disorder which is due to aging and wear and tear on a joint.

Arthritis involves the breakdown of cartilage. Cartilage protects the joint, this helps the two bones from rubbing upon each other.

Uncommon

Fibromyalgia is a syndrome in which a person has long term, body-wide pain and tenderness in the joints, muscles, tendons, and other soft tissues.

Rare

Myasthenia Gravis is a rare disorder of muscle weakness, affecting approximately 70,000 individuals in the United States.

Diseases and Disorders of Muscles

How Common in the U.S.

Osteoarthritis

(most prevalent type of Arthritis)

Arthritis

Fibromyalgia

Myasthenia gravis

Muscles Up-Close

Pig and Human Muscles

Cheetah/Cat and Human Muscles

What is going on at the Molecular Level

Cardiac Muscle

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Finally, the ATP is broken down into ADP and Pi, which causes the Myosin heads to cock back, ready for another power stroke.

Contracted

Skeletal Muscle

Muscles

Arden Coleman

Muscle Contraction

The ADP and Pi, which cause the Myosin heads to cock back, are left behind during the power stroke.

Smooth Muscles

Calcium ions bind to Troponin complex.

Relaxed

Three different types of muscles

The Myosin heads are now in contact with Myosin binding sites. The Myosin heads will move the thin filament, contracting the muscle.

What is going on at the Molecular level?

The introducion of ATP causes the Myosin heads to release the Actin.