EyeWire

WHY?

WHAT IS IT

good for

• Reconstruction time for one cell = 50 hours

• 80 billion cells in the brain

• Calculation:
• team of 100 people
• work 24/7
• 500.000 years to map one brain

• Game to help scientists

• analyse nerve connections of a mouse’s retina

• how neurons are connected

• how a mammal’s retina captures movements

EyeWire

A game to map the brain

Sources

ACHIEVEMENTS

• http://eyewire.org/explore

• https://en.wikipedia.org/wiki/Eyewire

• http://www.zeit.de/2013/38/citizen-science-eyewire-seti

• http://www.golem.de/news/eyewire-funktionsweise-des-auges-durch-onlinespiel-entschluesselt-1405-106293.html

• 120.000 players from nearly 150 countries

• EyeWirers have reconstructed more than 100 neurons so far

HOW?

GOALS

• Virtually cobble nerve connections of the retina together

• Using high-resolution microscope images

• Two-dimensional scans of the retina

--> three-dimensional cube

• Mark development of the neurons

• Scroll through the scans in the cube

• Discover the structures of the neurons

• Mark them

• Reconstruct three-dimensional shapes of retinal neurons

• Two-dimensional images

• Identify the synapses

• Map connections between neurons in the retina

• Reconstruct the connectome

• Relate connectivity with known activity of the neurons