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Parkinson Disease

The SECONDary motor

symptoms

-"Freezing" -Micrographia

-Mask Expression

The early symptoms

• Loss of sense of smell

• Behavior disorder (sleep disorder)

• Mood disorders

• Orthostatic hypotension

Mateo Nieto

What is the Parkinson’s Disease?

Famous faces of pd

-Chronic and (slow) progressive movement disorder

-Malfunction and death of vital nerve cells in the brain

Muhammad Ali

The boxing champion began showing signs of Parkinson’s disease shortly after retiring from boxing in 1981 (diagnosed with the disease in 1984 at the age of 42). His doctors are not entirely sure, but his PD may be the result of repeated blows to the head during boxing matches.

Parkinson Disease

Michael J. Fox

VOCABULARY

Most famous for his role as Marty McFly in the Back to the Future movies, he was diagnosed with PD in 1991 at the age of 30, seven years later, he went public with his diagnosis. He eventually established the Michael J. Fox Foundation, which raises money for research of PD.

spoon V.S. PD

-Even though there is no cure (actually), there are treatment options such as medication and surgery to manage its symptoms.

Causes

-The causes remain unknown

-Combination of genetic and environmental factors.

-There is a 2-4 % risk for people of 60 years old, compared with 1-2% in the general population. (Get PD)

Dopamine : a chemical that sends messages to the part of the brain that controls movement and coordination.

PD : Contraction of "Parkinson Disease".

Substantia Nigra : It is a brain structure located in the midbrain that plays an important role in movement. (NIGRA -> DARK PART OF THE BRAIN)

Orthostatic hypotension : low blood pressure when standing up.

PARKINSON IN NUMBERS

-1,000,000 Americans live with PD (Same # of people Montana State)

-Approximately 60,000 Americans are diagnosed with PD each year (this number does not reflect the cases that go undetected).

-An estimated 7 to 10 million people worldwide are living with Parkinson's disease.

-Men are 1 and 1/2 times more likely to have PD than women.

-PD "costs" $100,000 dollars per patient each year (medication-surgery).

PD primarily affects neurons in the Substantia Nigra. Some of these dying neurons produce dopamine. As PD progresses, the amount of dopamine produced decreases, leaving a person unable to control movement normally.

Pope John Paul II

The second-longest serving pope in history, was diagnosed with PD near 2003 when The Vatican confirmed that Pope John Paul II suffered from this chronic disease. His supremacy lasted over 26 years before coming to an end in 2005, when he died of an infection at the age of 84.

What are Parkinson’s Symptoms?

Bob Hoskins

The Primary motor

symptoms

Thank you

The Golden Globe Award winner, Bob Hoskins was forced to retire from acting after his PD diagnosis in 2012. Bob Hoskins appeared in numerous movies throughout his 40-year acting career, including The Long Friday, Mona Lisa and Who Framed Roger Rabbit.

-Resting Tremor

-Bradykinesia

-Rigidity

-Postural Instability

ECG

62

bpm

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