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Vesicular Transport

$1.25

March 4, 2014

by Sydney Schaefer

Process

Exocytosis

Receptor-Mediated Endocytosis

Endocytosis

a part of the plasma membrane is invaginated and pinched off forming a membrane-bounded vesicle called an endosome during endocytosis.

After the binding of a ligand to plasma membrane-spanning receptors,

-a signal is sent through the membrane, leading to membrane coating, and forming of a membrane invagination.

-The receptor and its ligand are then opsonized in clathrin-coated vesicles.

- Once opsonized, the clathrin-coated vesicle decoats and single vesicles fuse together to form the early endosome.

-Since the receptor is internalized with the ligand, the system is saturable and

-uptake will decline until receptors are reused to the surface.

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The membrane bound vesicles involved in exocytosis, contain soluble proteins to be secreted to the outside area, as well as membrane proteins and lipids that are sent to become components of the cell membrane.

Endocytosis is...

- an energy process by which cells absorb molecules such as proteins by consuming them.

-It's used by all cells of the body because most substances important to them are large polar molecules that cannot pass through the hydrophobic plasma or cell membrane.

-process where cells internalize molecules

-by the inside budding of plasma membrane vesicles

-containing proteins with receptor sites certain to the molecules being internalized.

Exocytosis, is...

- the durable, energy-consuming process

-by which a cell directs the contents of secretory vesicles

-out of the cell membrane and into the extracellular space.

-It is the opposite of endocytosis. -Instead of consuming the moleucles, it exports them.

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Phagocytosis

It is possible for cells other than dedicated phagocytes to engage in phagocytosis.

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  • the process by which a cell, often a phagocyte or a protist takes in a solid particle to form an inside vesicle known as a phagosome.
  • Phagocytosis is a certain form of endocytosis

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Pinocytosis

- pinocytosis is nonspecific in the substances that it transports

- it generates very small amounts of ATP from the wastes of alternative substances such as lipids

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-a mode of endocytosis

-in which small particles are brought into the cell, forming an invagination

-it is then suspended within small vesicles

-Pinocytosis is non-specific and non-absorptive

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