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IN VITRO GAMETOGENESIS
11
Transcript
Definition
Process
IN VITRO GAMETOGENESIS
Criticism
Say Patrick, Rauscher Katharina, Perea Valentina
'Pros'
References
IVG - Definition
Topic
- = In Vitro Gametogenesis
- skin cell -> germ cell -> baby
- experimented on mice
- possible in ~5 years for humans
- requires CRISPR & IVF
How does it work?
- successful in mice
- humans: 3-Person-Baby
- e.g.: sperm cell + DNA-package + egg cell
- recently discovered: human skin cell -> germ cell
- early problem: remaining virus-DNA
Topic
Figure 1: Sunshine Egg Donor Agency, 'In Vitro Gametogenesis IVG - Embryology Way to Design a Baby', https://www.eggdonors.asia/wp-content/uploads/2019/04/ivf-to-ivg-1.jpg, [24.11.2020]
Positive Aspects
Topic
- solves infertility problems
- every gender could reproduce together
- used for research purposes
- prenatal selection (prevention of diseases)
Criticism
- designer babies
- unnatural
- less adoptions
- long term risks (physical and psychosocial)
Topic
References
Topic
- Sarah C.P. Williams, 'UCLA research could be step toward lab-grown eggs and sperm to treat infertility', https://stemcell.ucla.edu/news/ucla-research-could-be-step-toward-lab-grown-eggs-and-sperm-treat-infertility, 2020, [24.11.2020]
- Sonia M Suter, 'In vitro gametogenesis: Just another way to have a baby?', Journal of Law and the Bioscienes, v. 3, page 1-33, 2015
- JR Minkel, 'Stem Cells from Skin Cells', https://www.scientificamerican.com/article/stem-cells-from-skin-cells/ [24.11.2020]
- Jera Weltner, Diego Balboa, Shintaro Katayama et al., 'Human pluripotent reprogramming with CrispR activators', Nature Communications, v. 9, article 2643, 2018
- Hana Benchetrit, Mohammad Jaber, Valery Zayat, et al., 'Direct Induction of the Three Pre-implantation Blastocyst Cell Types from Fibroblasts', Cell Stem Cell, v. 24, page 983-994, 2019
- Bulman May, 'Number of adoptions plummet due to IVF treatment success', Independent, https://www.independent.co.uk/news/uk/home-news/adoption-numbers-down-ivf-children-care-fertility-treatment-families-cfcas-a8615726.html, 2018, [25.11.2020]
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