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Recombivax HB Vaccine
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Hepatitis B Vaccine (Recombivax HB)
Invention
Topic
Hepatitis B is a severe liver infection. In 1969, four years after Dr Baruch Blumberg discovers the hepatitis B virus, he works with microbiologist Irving Millman to develop the first hepatitis B vaccine. I'm going to talk about the Recombivax HB by Merck & Co, USA.
Development
Topic
RECOMBIVAX HB is approved for use in individuals of all ages. In May 1986, the vaccine Recombivax HB was approved for marketing in West Germany; approval by the United States Food and Drug Administration followed two months later.
Recombivax HB marked a milestone in the development of medical biotechnology. Manufactured by Merck Sharp & Dohme, it was the first vaccine to be produced using recombinant DNA technology, and only the third recombinant product to be licensed for human use.
A portion of the hepatitis B virus gene, coding for HBsAg, is cloned into yeast, and the vaccine for hepatitis B is produced from cultures of this recombinant yeast strain according to methods developed in the Merck Research Laboratories.
How it spreads
Topic
Hepatitis B is a serious liver infection caused by the hepatitis B virus (HBV).
The virus is passed from person to person through blood, mother to child, unprotected sex with someone who's infected, semen or other body fluids and sharing of needles. It does not spread by sneezing or coughing.
How it works
Topic
The vaccine works by causing your body to produce its own protection (antibodies) against the disease.
Hepatitis B vaccine will not protect against infection with hepatitis A, C, and E, or other viruses that affect the liver. It may also not protect against hepatitis B if you are already infected with the virus, even if you do not yet show symptoms.
Sources
Topic
https://www.drugs.com/mtm/recombivax-hb-dialysis-formulation.html
https://www.medicinenet.com/hepatitis_b_vaccine-injection/article.htm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482909/