Introducing
Your new presentation assistant.
Refine, enhance, and tailor your content, source relevant images, and edit visuals quicker than ever before.
Trending searches
About 1.7 million/yr or 6% of admissions
270,000 deaths or ~15% mortality
40%-50% mortality if it progresses to shock
Most expensive condition in American Healthcare - >$24 Billion
Sepsis
Organ dysfunction caused by disregulated host response to an infection
Septic Shock
Circulatory and cellular/metabolic dysfunction associated with higher risk of mortality
Endotoxins/LPS
Macrophage Activation
TNF/IL/Interferon
Fever/Tachy NO/Vasodilation
Cellular Hypoxia
Requires Infection AND Inflammation
Doesn't require "Bad" infection
Organ dysfunction is host mediated