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Polycystic Kidney Disease
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Polycystic Kidney Disease
Emily Krkoska
Disease
- inherited disorder
Disease
pathogenesis
This disease most likely comes from defects in the primary cilium.
pathogenesis
Pathophysiology
PKD develops in atrophic and scarred end-stage kidneys with non-cystic forms of renal disease
Pathophysiology
Genetic Predisposition
People with this condition are born with one mutated copy of the PKD1 or PKD2 gene in each cell.
Genetic Predisposition
Prevention
There is no way to prevent PKD, however keeping the kidney healthy (by managing blood pressure) can help prevent any complications that may come with PKD.
Prevention
Contributing factors
Diabetes and high blood pressure are the two leading causes of kidney disease.
Contributing factors
Diagnostic tests performed
An imaging test, such as an ultrasound, CT, or MRI scan
Diagnostic tests performed
Signs and symptoms
Pain in the lower half of the back or on the side, with or without a fever, Pain in the belly, Blood in the urine, Kidney stones
Signs and symptoms
Medical or surgical management
There is no cure for autosomal dominant PKD. Treatment involves managing symptoms (pain, headaches, high blood pressure, urinary tract infections) and preventing complications, as well as slowing the progression of the disease.