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Hight serum levels of betatrophin in metabolic subjects in UAE
10
Transcript
Betatrophin levels are increased in obese and metabolic syndrome subjects from the UAE
Done by : Shreena Ahmed B. & Asma Bachir
Department: Medical labs
Supervisor : prof. Samir Awadallah
Betatrophin
- ANGPTL8
- Peptide hormone
- Atypical member of ANGPTL8
Introduction
Obesity
Based on : BMI , Waist circumference
Obesity
Metabolic syndrome
Metabolic syndrome
Previous studies
Previous studies
Aim of study
- It was not previously studied in UAE
- So,The aim of our study was to conduct the correlation between betatrophin in metabolic syndrome individuals in UAE
Aim of studies
Methods
- 277 samples were recruited from volunteers
- Fasting blood samples were collected from each individual based on specific measurements
Methods
Age
Gender
Standards
Parameters
Blood pressure
waist circumference
weight and height
- BMI were calculated using the height and weight
Samples were centrifuged
Refrigerated at -80 degrees
We measured the glucose levels and the lipid profile using Pchem machine
We measured the Betatrophin using an automated ELISA
Process
Analysis
General characteristics of subjects (n = 277)
Results
Clinical and Biochemical features of all subjects, (n = 277).
Biochem features
Betatrophin levels
Betatrophin
mets scores
Mets score
Conclusion
we concluded that serum betatrophin is increased in obese individuals as well as in individuals with metabolic syndrome
Further studies
Conclusion
Study the association of betatrophin with insulin levels and insulin resistance among type1 and type 2 diabetes.
Acknowledgment
Thanks to :
Prof. Samir Awadallah
Ms. Hema Unnikannam
Acknowledgment
Thank you
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