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Využitie: biologické, farmácia
blokácia:
1-aryl-1,4-dihydropyridín-3,5-dikarboxylovej kyseliny = ďalší blokátor
A.Locatelli a spol.:Ligand Based Approach to L-Type Calcium Channel by Imidazo[2,1-b]thiazole-1,4-Dihydropyridines: from Heart Activity to Brain Affinity.J. Med. Chem. 2013, 56, 10, 3866–3877. doi: 10.1021/jm301839q
Ann Riya Ninan, Ritchu Babbar, Sonia Dhiman , Thakur Gurjeet Singh, Kirandeep Kaur, Vanshika Dhiwan: A Systematic Review on 1, 4-Dihydropyridines and its Analogues: An Elite Scaffold. Biointerface Research in Applied Chemistry 12 (3): 3117-3134, (2022)
A P, Makam P. 1,4-Dihydropyridine: synthetic advances, medicinal and insecticidal properties. RSC Adv. 2022 Oct 12;12(45):29253-29290. doi: 10.1039/d2ra04589c
Brahmachari, Goutam Demain, Arnold L. Adrio, Jose L.. (2017). Biotechnology of Microbial Enzymes - Production, Biocatalysis and Industrial Applications - 17.3.2.2 Potassium Channel Openers. (pp. 13). Elsevier. Retrieved from https://app.knovel.com/hotlink/pdf/id:kt0112S1I5/biotechnology-microbial/potassium-channel-openers
Miyase Gözde Gündüz; Sanja J. Armaković; Cagatay Dengiz; Muhammad Nawaz Tahir; Stevan Armaković: Crystal structure determination and computational studies of 1,4-dihydropyridine derivatives as selective T-type calcium channel blockers. Journal of Molecular Structure 1230, 129898 (2021)
Dmitriy Khrustalev, Azamat Yedrissov, Anastassiya Khrustaleva, Marlen Mustafin, Kamilla Bekisheva, An efficient method for the synthesis of 1,4-dihydropyridine derivatives in a flow microwave reactor, Materials Today: Proceedings, 2023, ISSN 2214-7853