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Keith Megara Osores, Adtrià Pladevall, Maria Plana i Maria Poch
PATIENT:
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SYMPTOMS:
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DIAGNOSIS:
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pyrimidine ring with amino group
sulphur thiazole ring
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Pyruvate Acetyl-CoA
Glycolysis Krebs cycle
Pyruvate decarboxilation and union to the lipoic acid of the next enzime
Acetylcholine
Synthesis
Myelin
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Citric acid cycle
Glutamate
Gamma–aminobutyric
acid (GABA)
Aspartate
Acetyl CoA NADH+FADH2 ATP
Picture source: 1.https://en.wikipedia.org/wiki/File:Citric_acid_cycle_with_aconitate_2.svg 2. https://www.flaticon.es/icono-gratis/energia-renovable_355423
Glucose
Phentose phosphate
pathway
Glucose-6-phosphate
TRANSKETOLASE
Ribose-5-phospate NADPH
+
Nucleic acids
Complex sugars
Coenzymes
Steroids
Amino acids
Fatty acids
Glutathione
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THIAMINE DEFICIENCY DISEASES
Wernicke-Korsakoff Syndrome
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Intravenous thiamine
Thiamine rich foods
Soybeans
Tuna
Whole grains
Peas
Pork
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NO thiamine NO ATP
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Recent studies show a close relation between thiamine deficiency and
Alzheimer
Cancer
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En.wikipedia.org. (2019). Thiamine. [online] Available at: https://en.wikipedia.org/wiki/Thiamine [Accessed 01 Dec. 2019].
Emedicine.medscape.com. (2019). Beriberi (Thiamine Deficiency): Practice Essentials, Pathophysiology, Etiology. [online] Available at: https://emedicine.medscape.com/article/116930-overview [Accessed 13 Nov. 2019].
Emedicine.medscape.com. (2019). Beriberi (Thiamine Deficiency): Practice Essentials, Pathophysiology, Etiology. [online] Available at: https://emedicine.medscape.com/article/116930-overview [Accessed 13 Nov. 2019].
Emedicine.medscape.com. (2019). Beriberi (Thiamine Deficiency): Practice Essentials, Pathophysiology, Etiology. [online] Available at: https://emedicine.medscape.com/article/116930-overview [Accessed 13 Nov. 2019].
Emedicine.medscape.com. (2019). Beriberi (Thiamine Deficiency) Treatment & Management: Approach Considerations, Activity. [online] Available at: https://emedicine.medscape.com/article/116930-treatment [Accessed 17 Nov. 2019].
Emedicine.medscape.com. (2019). Wernicke-Korsakoff Syndrome: Background, Etiology, Pathophysiology. [online] Available at: https://emedicine.medscape.com/article/288379-overview#a3 [Accessed 5 Dec. 2019].
Anon, (2019). Responses of the mitochondrial alpha-ketoglutarate dehydrogenase. [online] Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753422/ [Accessed 6 Dec. 2019].
Anon, (2019). Alpha-ketoglutarate dehydrogenase. [online] Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569585/ [Accessed 16 Nov. 2019].
Biocyc.org. (2019). MetaCyc 2-ketoglutarate dehydrogenase complex. [online] Available at: https://biocyc.org/META/new-image?object=CPLX66-42 [Accessed 20 Nov. 2019].
Medscape.com. (2019). What is included in the treatment of beriberi (thiamine deficiency)?. [online] Available at: https://www.medscape.com/answers/116930-91240/what-is-included-in-the-treatment-of-beriberi-thiamine-deficiency [Accessed 13 Nov. 2019].
Kenneth Osiezagha, R. (2019). Thiamine Deficiency and Delirium. [online] PubMed Central (PMC). Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659035/ [Accessed 8 Dec. 2019].
Emedicine.medscape.com. (2019). Wernicke Encephalopathy: Practice Essentials, Etiology, Epidemiology. [online] Available at: https://emedicine.medscape.com/article/794583-overview [Accessed 18 Nov. 2019].
Medical News Today. (2019). Wernicke-Korsakoff syndrome: Symptoms, causes, and treatment. [online] Available at: https://www.medicalnewstoday.com/articles/220007.php#treatment [Accessed 30 Nov. 2019].
Linus Pauling Institute. (2019). Thiamin. [online] Available at: https://lpi.oregonstate.edu/mic/vitamins/thiamin [Accessed 2 Dec. 2019].
Pubs.niaaa.nih.gov. (2019). The Role of Thiamine Deficiency in Alcoholic Brain Disease. [online] Available at: https://pubs.niaaa.nih.gov/publications/arh27-2/134-142.htm [Accessed 8 Dec. 2019].
Healthline. (2019). Wernicke-Korsakoff Syndrome: Risks, Causes, Symptoms, and More. [online] Available at: https://www.healthline.com/health/wernicke-korsakoff-syndrome#outlook [Accessed 13 Nov. 2019].