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Cholera

By: Aidan Ayala

What is it?

Cholera is a diarrheal illness caused by an intestinal infection with the Vibrio Cholerae bacteria. People can get this infection when they eat or drink an item with this bacteria in it. The symptoms of this illness can sometimes be mild or hvae none at all, but in other cases, it can be severe and life-threatening.

Cholera

Graphics

Tissue affected by Cholera

Graphics

normal cell signaling pathways

Faulty cell signaling pathways

Core Symptoms

Symptoms can include:

Vomitting

Diarrhea

Dehydration

Mucle Cramps

Shock

Restlessness and Irritability

Info

The direction headed

Scientists are developing improved vaccines for Cholera. And are currently devising new drugs based on molecules and natural products to treat Cholera.

Current direction in research

Correct mechanism

Cholera toxin and other types of toxin produce a variety of extracellular prodeucts that have deleterious effects on eukaryotic cells.

Correct/ incorrect mechanism

Incorrect mechanism

The toxin cuases overactivation of signalling pathway that controls the activity of Cholride channel proteins.

Work cited

"Illness and Symptoms | Cholera"CDC, https://www.cdc.gov/cholera/illness.html#:~:text=Cholera%20is%20an%20acute%20diarrheal,be%20severe%20and%20life%2Dthreatening. Accessed 15 Nov. 2022

"Cholera" World Health Organization, https://www.who.int/news-room/fact-sheets/detail/cholera Accessed 15 Nov. 2022

"Cholera - Symptoms and causes" Mayo Clinic, https://www.mayoclinic.org/diseases-conditions/cholera/symptoms-causes/syc-20355287?utm_source=Google&utm_medium=abstract&utm_content=Cholera&utm_campaign=Knowledge-panel Accessed 15 Nov. 2022

Citations

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