Bleeding and
Thrombosis
SECLON, ALYSSA MARIE P.
POST-GRADUATE INTERN
HEMOSTASIS
Hemostasis
- Vascular Constriction
- Formation of Platelet Plug
- Formation of a Blood Clot
- Eventual growth of fibrous tissue into blood clot to close the hole in the vessel
Primary Hemostasis:
Sequence of Events:
- Platelet Adhesion
- Platelet Activation
- Platelet plug formation
Key Components:
- Endothelial Cells
- Platelets
- Adhesive proteins: vWf and collagen, and facilitators including thrombin
Primary
Final Result:
Formation of a Platelet Plug
Topic 2
Approach to
Patient
Topic 3
Laboratory
Evaluation