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Merci beaucoup pour votre attention!

belcardoso@hotmail.com

@institutodeolhoshc

Masc, 73 a

24/11/17

18/11/16

Chandler syndrome

Chandler Syndrome

J.P., female, 26 yo

OD

Early Stage

A.F., male, 39 yo

PÓS-RADIOTHERAPIE EXTERNE BILATERAL

OEIL DROIT

OEIL GAUCHE

IMAGES IN ICE SYNDROME

Isabel Habeyche Cardoso

Coogan Reese

Cogan-Reese Syndrome

Iris Nodules

C.M., female, 10 yo

Neurofibromatosis

LE

MUITO OBRIGADA!

MERCI BEAUCOUP!

Porto Alegre - RS- Brazil

belcardoso@hotmail.com

www.iohc.com.br

T 10-11h

T 7-8h

ICE SYNDROME

* Unknown etiology: there are theories that a viral infection (Herpes simplex virus or Epstein-Barr virus) leads to a low grade inflammation at corneal endothelium, resulting in its unusual epithelial-like activity.

* Corneal endothelial PCR tests >> higher % of HSV DNA comparing to normal controls.

* Rare disorder, unilateral, non-hereditary, adults (F, 30-40 yo)

* Varying combinations of corneal edema (due to endothelium abnormalies), iris atrophy (holes), peripheral anterior synechiae (PAS), and secondary glaucoma.

* Lower vision due to cornea decompensation and glaucoma

Cogan-Reese Syndrome

E.P., female, 48 yo

12h

RE

10-11h

RE

9h

RE

Progressive Essential Iris Atrophy x Amelanotic Iris Nevus

Progressive Essential Iris Atrophy

D.B., female, 28 yo

RE

LE

Scanning Electron Microscopy

ICE SYNDROME

Scanning Electron Microscopy

Cogan-Reese Syndrome

C.K. female, 59 yo

RE

LE

Spectrum of 3 clinical entities:

* Progressive Essential Iris Atrophy

Corectopia, polycoria, iris atrophy / hole formation, ectropion uveae, PAS, ED and corneal edema

* Cogan-Reese Syndrome

Nodules and iris atrophy, "iris nevus syndrome", ED, PAS, corneal edema may ocur

* Chandler Syndrome (50%)

Early corneal edema, ED, iris findings less common, PAS

ENDOTHELIAL DYSTROPHY

"hammered silver" or "beaten bronze"

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