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The culprit is the varicella-zoster virus. Primary infection with this virus causes chickenpox (varicella). At this time the virus infects nerves (namely, the dorsal root ganglia) where it remains latent (lies low) for years. It can then be reactivated to cause shingles with blisters over the distribution of the affected nerve accompanied by often intense pain and itching. Herpes zoster is more frequent with increasing age
A dermatome is an area of skin that is mainly supplied by a single spinal nerve. There are 8 cervical nerves (note C1 has with no dermatome), 12 thoracic nerves, 5 lumbar nerves and 5 sacral nerves. Each of these spinal nerves relay sensation from a particular region of the skin to the brain.
Hz is a common disease with highest burden in older adults who frequently have at least one chronic disease.
HZ is primarily disease of nerve tissue but the acute and longer term manifestations require multidisciplinary knowledge and involvement in their management.