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Life Cycle of Red Blood Cell
1
- Erythropoiesis is the formation of RBCs
- It begins in the red bone marrow, this process is known as Hematopoietic stem cells (HSC)
- HSC differentiate into proerythroblasts, which becomes RBCs
- Proerythroblasts undergo mutation to become erythroblast. These cells synthesize hemoglobin, which is a protein that transport oxygen.
Erythroblast mature into normoblast.
Normoblast mature and eject thier nucleus to make room for hemoglobin.
The Normoblast without their nucleus become reticulocytes and they enter the blood stream.
Reticulocytes lose their remaining organelles and become mature erythrocytes.
References
Formation
National Center for Biotechnology Information (NCBI):
* NCBI provides comprehensive information on erythropoiesis, the process of red blood cell formation.
* Link: NCBI - Erythropoiesis
American Society of Hematology:
* The American Society of Hematology offers detailed explanations about the life cycle of red blood cells and the process of hemoglobin recycling.
* Link: American Society of Hematology - Red Blood Cells
National Heart, Lung, and Blood Institute (NHLBI):
* NHLBI provides insights into how red blood cells are produced, their function, and how they are removed from the bloodstream.
* Link: NHLBI - Blood
Red blood cells transport oxygen from the lungs to all parts of the body and help remove carbon dioxide.
Blood Formation Process
Name: Ardetha King
Course: Anatomy refresher
Instructor: Dr. Lisa Rinke
Date: 6/16/24
Formation of Red Blood Cell
Blood is formed through a complex process involving the production of various blood cells in the bone marrow.
Red blood cells are produced in the bone marrow through a process called erythropoiesis.
Life Cycle of Red Blood Cell
Destruction of Red Blood Cell
From Formation to Removal
When red blood cells become old or damaged, they are removed by the spleen and liver, and their components are recycled.
The spleen filters out old and damaged RBCs. Macrophages in the spleen break down these RBCs by phagocytosis.