Introducing
Your new presentation assistant.
Refine, enhance, and tailor your content, source relevant images, and edit visuals quicker than ever before.
Trending searches
1. General information
2. Symptoms
3. Risk factors
4. Diagnosis
5. Treatment
6. Sources
https://creakyjoints.org/about-arthritis/gout/gout-treatment/gout-treatment-reduce-uric-acid-crystal-deposits/
Hyperuricemia
Hyperuricemia
Uric acid accumulation in joints
Hyperuricemia
Formation of monosodium urate crystals
Uric acid accumulation in joints
Hyperuricemia
Formation of monosodium urate crystals
Uric acid accumulation in joints
Inflammatory response to the crystals
Hyperuricemia
Formation of monosodium urate crystals
Uric acid accumulation in joints
Acute/chronic gouty arthritis
Inflammatory response to the crystals
Underexcretion of uric acid
Genetic factors
Lactic acidosis
Underexcretion of uric acid
Overproduction of uric acid
Genetic factors
Lactic acidosis
Mutations in the gene for X-linked PRPP synthetase --> increased Vmax
Gout symptoms include:
https://www.rheumatologyadvisor.com/home/topics/gout/patient-reported-gout-attack-intensity-score-may-be-reliable-for-use-in-clinical-studies/
Red meat
Red meat
Organ meats
Red meat
Organ meats
Animal proteins
Red meat
Organ meats
Animal proteins
Seafood
There is no cure!
Acute attacks: Anti- inflammatory agents
Colchicine --> Prevents formation of microtubules
Uricosuric agents eg. probenecid or sulfinpyrazone --> Increase renal excretion of uric acid
Allopurinol --> Inhibition of uric acid synthesis (xanthine oxidase)
Lippincott page 299ff.
Lecture slides
https://www.cdc.gov/arthritis/basics/gout.html
https://www.mayoclinic.org/diseases-conditions/gout/diagnosis-treatment/drc-20372903