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Polioemcephalomacia (PEM)

Calista Heley

Last Update: 04/21/2018

SUMMARY

SUMMARY

PEM affects the CNS and causes fluid build-up in the brain. The background from Kansas State is of a calf's brain that was effected by PEM.

C

CCET

CCET

E

T

CAUSE 1

Tyamine deficiency

Too much thiaminases produced in the rumen (breaks down thiamine)

CAUSE 1

If the rumen increases in consuming plants that contains thiaminases (horsetail, some ferns, ect.)

CAUSE 2

Too much sulfur is consumed

Can be from water, feed and/or forages

CAUSE 2

Some common plants to watch out for are canada thistle, alfalfa, laibsquater, ect.

EFFECTS

Camelids, deer, cattle, sheep, and goats

EFFECT

Does not vary by age. Is not transferable between animals of same or different species.

PEM is not zootonic

TREATMENTS

If in the early stage, decrease sulfur availability, and drench with thiamine and feed good quality hay.

TREATMENT

If caused by inactive rumen microbes, oral supplements are needed until rumen is functioning as normal.

Injections of thiamine are neccessary in late stage. If animal has had too much brain damage the animal is culled.

SYMPTOMS

SYMPTOMS

STAR GAZING

STAR GAZING

EFFECTED ANIMALS TEND TO REAR THEIR HEAD BACK AND 'STAR GAZE'.

THEY ALSO CAN HEAD BUTT POSTS, WALLS, ECT. MAY SEEM OFF IN ACTIONS

**SHOWN ON PREVIOUS SLIDE ASWELL

BLINDNESS STAGGERING

BLINDNESS/STAGGERING

ANIMALS GO BLIND

THEIR GAIT CHANGES FROM LACK OF MUSCLE COORDINATION.

CONVULSIONS SALAVATION

CONVULSIONS/ SALIVATION

IF PEM HAS PROGRESSED ENOUGH, THE ANIMAL WILL HAVE SUIZURE LIKE ACTIONS

START TO FOAM AT THE MOUTH FROM OVER SALIVATION.

OTHER

OTHER

~ ISOLATION

~ DEPRESSION

~ LACK OF APPITITE

~ DIAREHHA

~ FEVER

~ RECUMBANCY

~ DEATH

TIMELINE

TIMELINE

It is good to note that depending on severity, the animal's timeline could be half of this

DAY 1

DAY 1

THE FIRST THINGS THAT WOULD BE NOTICED ARE AS FOLLOWS:

~ ISOLATION

~ STOP EATING

~ FACIAL/EAR TWITCHING

~ STAR GAZE

DAY 2

DAY 2

~ STAR GAZE

~ BLINDNESS

~ MUSCLE TWITCH

~ DIAREHHA

~ SOME SALIVATION

DAY 3-4

DAY 3-4

~ SEVERE SALIVATION

~ HEAD PRESSING

~ TEETH GRINDING

~ SEIZURES

~ DEATH

CITATIONS

CITATIONS

IMAGES

IMAGES

Clark, Gary, and Heritage Te Manatu Taonga. “Polioencephalomalacia in Sheep.” Te Ara Encyclopedia of New Zealand – Te Ara Encyclopedia of New Zealand, Ministry for Culture and Heritage Te Manatu Taonga, 14 Nov. 2012, teara.govt.nz/en/photograph/17440/polioencephalomalacia-in-sheep.

“Polioencephalomalacia (PEM).” Capacity Building Grant, cahsspvd.pvamu.edu/animal-health-issues/polioencephalomalacia/.

Maryland Small Ruminant Page, www.sheepandgoat.com/summer2016?lightbox=image_j2s.

“Polioencephalomalacia (PEM) Vit B1 (Thiamine) Deficiency.” South African Mohair Growers' Association (SAMGA), www.angoras.co.za/article/polioencephalomalacia-pem.

frecko.id.au. “CASE NOTES.” Polioencephalomalacia, www.flockandherd.net.au/cattle/reader/rape-blindness.html.

“Chapter 13. Common Bovine Diseases.” PDF, petsdocbox.com/Veterinary_Medicine/71029946-Chapter-13-common-bovine-diseases.html.

INFO

INFO

“Overview of Polioencephalomalacia - Nervous System.” Merck Veterinary Manual, www.merckvetmanual.com/nervous-system/polioencephalomalacia/overview-of-polioencephalomalacia.

Polioencephalomalacia, ag.ansc.purdue.edu/sheep/ansc442/Semprojs/2002/neurological/polio.htm.

“Thiamine Deficiency Induced Polioencephomalacia (PEM) of Sheep and Cattle.” Agriculture and Food, www.agric.wa.gov.au/livestock-biosecurity/thiamine-deficiency-induced-polioencephomalacia-pem-sheep-and-cattle.

“F643 Polioencephalomalacia (PEM).” Polioencephalomalacia, infovets.com/books/smrm/F/F643.htm.

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