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PEM affects the CNS and causes fluid build-up in the brain. The background from Kansas State is of a calf's brain that was effected by PEM.
Tyamine deficiency
Too much thiaminases produced in the rumen (breaks down thiamine)
If the rumen increases in consuming plants that contains thiaminases (horsetail, some ferns, ect.)
Too much sulfur is consumed
Can be from water, feed and/or forages
Some common plants to watch out for are canada thistle, alfalfa, laibsquater, ect.
Camelids, deer, cattle, sheep, and goats
Does not vary by age. Is not transferable between animals of same or different species.
PEM is not zootonic
If in the early stage, decrease sulfur availability, and drench with thiamine and feed good quality hay.
If caused by inactive rumen microbes, oral supplements are needed until rumen is functioning as normal.
Injections of thiamine are neccessary in late stage. If animal has had too much brain damage the animal is culled.
EFFECTED ANIMALS TEND TO REAR THEIR HEAD BACK AND 'STAR GAZE'.
THEY ALSO CAN HEAD BUTT POSTS, WALLS, ECT. MAY SEEM OFF IN ACTIONS
**SHOWN ON PREVIOUS SLIDE ASWELL
ANIMALS GO BLIND
THEIR GAIT CHANGES FROM LACK OF MUSCLE COORDINATION.
IF PEM HAS PROGRESSED ENOUGH, THE ANIMAL WILL HAVE SUIZURE LIKE ACTIONS
START TO FOAM AT THE MOUTH FROM OVER SALIVATION.
~ ISOLATION
~ DEPRESSION
~ LACK OF APPITITE
~ DIAREHHA
~ FEVER
~ RECUMBANCY
~ DEATH
It is good to note that depending on severity, the animal's timeline could be half of this
THE FIRST THINGS THAT WOULD BE NOTICED ARE AS FOLLOWS:
~ ISOLATION
~ STOP EATING
~ FACIAL/EAR TWITCHING
~ STAR GAZE
~ STAR GAZE
~ BLINDNESS
~ MUSCLE TWITCH
~ DIAREHHA
~ SOME SALIVATION
~ SEVERE SALIVATION
~ HEAD PRESSING
~ TEETH GRINDING
~ SEIZURES
~ DEATH
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“Polioencephalomalacia (PEM).” Capacity Building Grant, cahsspvd.pvamu.edu/animal-health-issues/polioencephalomalacia/.
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“Chapter 13. Common Bovine Diseases.” PDF, petsdocbox.com/Veterinary_Medicine/71029946-Chapter-13-common-bovine-diseases.html.
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Polioencephalomalacia, ag.ansc.purdue.edu/sheep/ansc442/Semprojs/2002/neurological/polio.htm.
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“F643 Polioencephalomalacia (PEM).” Polioencephalomalacia, infovets.com/books/smrm/F/F643.htm.