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synthesis of tricyclic compound [heptoxdiazines]
commercialization of [clorpromazine] in France.
Sternbach decided to continue the studies on tricyclic compounds [heptoxdiazines]
Development of 40 new compounds with structural similarity to clorpromazine but results were negative.
Twist of chance
Ro 5-0690 was submitted for testing
Results came back POSITIVE
The synthesis
[chlordiazepoxide] was patented by Sternbach
Development of 40 new compounds
commercialization of [clorpromazine]
[Clordiazepoxide ] was patented
the discovery
synthesis of [heptoxdiazines]
continue the studies on tricyclic compounds.
find and test Ro 5-0690