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Sandifer

Syndrome

By: Tori Kleint

Overview...

  • What it is
  • When it starts/ what causes it
  • Diagnosis/ Treatment

What it is...

Sandifer syndrome is a paroxysmal dystonic movement disorder occurring in association with

gastroesophageal reflux

Where it starts...

  • Infancy or early childhood.
  • 1-3 minutes, 10 times a day

https://www.orpha.net/consor/cgi-bin/Disease_Search.php?lng=EN&data_id=10994&Disease_Disease_Search_diseaseGroup=sandifer&Disease_Disease_Search_diseaseType=Pat&Disease(s)/group%20of%20diseases=Sandifer-syndrome&title=Sandifer%20syndrome&search=Disease_Search_Simple

Body signs...

Abnormal posturing of head and neck, sever arching of spine.

https://www.youtube.com/watch?v=bWsr2D6pSX4

Other symptoms...

  • Vomiting
  • poor feeding
  • anaemia
  • epigastric discomfort
  • haematemesis (vomiting blood)
  • abnormal eye movement
  • Reflux oesophagitis (inflamation)

What causes it...

Compulsive movements caused by abdominal pain caused by acid reflux.

Some studies believe movements are to relieve pain.

https://rarediseases.info.nih.gov/diseases/9684/sandifer-syndrome

Diagnosis...

  • Association of gastroesophageal reflux.
  • The characteristic movement disorder.
  • Neurological examination is usually normal.

https://rarediseases.info.nih.gov/diseases/9684/sandifer-syndrome

Gastroesophageal reflux

Muscle at end of esophagus Does not close.

https://medlineplus.gov/gerd.html#summary

Psychogenic Movement Disorder

Unwanted movements or Spasms

https://www.youtube.com/watch?v=Tmy_ro-XBLE

https://www.bcm.edu/healthcare/care-centers/parkinsons/conditions/psychogenic-movement-disorders

Treatments...

  • Medication
  • Surgery

https://www.orpha.net/consor/cgi-bin/Disease_Search.php?lng=EN&data_id=10994&Disease_Disease_Search_diseaseGroup=sandifer&Disease_Disease_Search_diseaseType=Pat&Disease(s)/group%20of%20diseases=Sandifer-syndrome&title=Sandifer%20syndrome&search=Disease_Search_Simple

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