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BioCartilage Arthrex
2
Chase August
James Hamann
By Arthrex
The principle of BioCartilage is to serve as a scaffold over a micro fractured
defect, providing a tissue network that can potentially signal autologous
cellular interactions, reduces chance of donor cite morbidity by adding scaffold that progenitor cells can attach to.
Features
Benefits
Values
F: Contains the ECM native to the articular cartilage
B: Includes key components such as type II collagen, proteoglycans, and additional cartilaginous growth factors
V: Value to patient, induces tissue repair by undamaged cells at the site of injury and stimulates cellular migration to these areas
Autologus ECM
F: Increased surface area due to small particle size
B: Provides attachment sites for the patient’s bone marrow cells
V: Value to patient, facilitates progenitor cells ability to attach to the BioCartilage ECM aiding in cell differentiation and specialization
Increased Surface Area
F: Serves as a scaffold over a micro fractured defect.
B: Allows for adhesion of autologous progenitor cells
V: Value to patient and surgeon in the way it eliminates possibility of autograft rejection or disease transmission.
Scaffold
Hypothermic dehydration
F: Goes through a specialized, gently dehydration process (hypothermic dehydration) that allows the water content to be removed, while remaining in a liquid state.
B: Eliminates the need for lyophilization
V: Value to surgeon in minimizing cost, lyophilization can be costly and time consuming
F: Particle size of 100-300 microns
B: Improves its injectable nature after its mixed with an autologous blood solution
V: Value to surgeon, facilitates delivery to the defect site.
Small Particle size
F: Aseptically processed and packaged
B: Allows for ambient temperature storage with a shelf life of 5 years
V: Value to surgeon and patient in sterility and longevity of sterilization