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>Congenital
>Gender: Female (4:1 )
>Older women
>Men with radiation therapy of head and neck
>Iodine deficiency
>Excessive goitrogenic substances
>Hypo/Hyperthyroidism
>Adverse drug reaction
>Thyroiditis/Thyroid CA
Production of TSH
Release of thyroid hormone from the thyroid gland
Stimulation of the pituitary gland
Production of TRH
Interference with TRH-TSH thyroid hormone axis
>TSH assay
Imaging studies
>UTZ
>CT scan
>MRI
>PET
>FNAB/FNNAB
Hypertrophy of the thyroid gland
*Swelling in the neck
*Local compression causing dysphagia, dyspnea, stridor, plethora or hoarseness
*Pain
*S/Sx of Hypo/Hyperthyroidsm
Stimulation of the hypothalamus
Formation of thyroid nodule
Diffuse goiter
Enlargement of the whole thyroid
Metastasis of thyroid/inflammatory/malignant cells