Monosomy X

Or Turners Syndrome occurs 1 out of every 2,000-5,000 female births

• Caused by the absence (complete or partial) of one of the two X chromosomes.
• Not yet determined which genes on the X chromosome cause most signs and symptoms of Turner syndrome

Monosomy disorder which is not hereditary

The one exception to this observation is families with an X chromosome deletion, which is stable enough to be passed down through the generations and which also allows fertility

Symptoms

• Short stature
• Frequent Infertility
• Stocky build
• Difficultyh recognizing various spatial patterns
• Extra skin on the neck (webbed neck)
• Puffiness or swelling (lymphedema) of the hands and feet
• A low hairline at the back of the neck
• Low-set ears
• Hands and feet swollen or puffy at birth
• Soft nails that turn upward at the ends when at an older age
• Colored spots on the skin
• Problems with breast development
• Infertility
• Short fingers and toes
• Irregular rotation of wrist and elbow joints
• Heart defects
• Kidney problems.

Genetic Testing

• When a doctor suspects a person has Turner syndrome, he/she may be tested with a karyotype.
• The karyotype of monosomy X, which is the most common cause of Turner Syndrome, is termed "45X" -- meaning that a person has 44 autosomes and a single X chromosome. To which the usual female karyotype is 46, XX.

Genetic Testing Cont.

• The point when Turner syndrome is diagnosed will depend on the severity of the condition.
• A diagnosis of Turner syndrome can be made during prenatal testing.
• Girls with several Turner syndrome features may be diagnosed during infancy or early childhood.
• For women with milder Turner syndrome, a diagnosis may occur later in life.

Treatments And Cures

Because Turner syndrome is a problem with the chromosomes, there is no cure. Therefore, treatment focuses on controlling the features and symptoms of this condition.

Treatment options for Turner syndrome may include:

Regular screening

Medications

Surgery

Counseling and support.

Regular screening

Medications

Surgery

Counseling and support.

Life

• Most women with Turner syndrome can live relatively normal lives.
• Their lives are mainnly dependant on other conditions that are present or may be present.
• Care must be taken to regularly monitor them for the health problems that are associated with Turner syndrome. For example, heart or kidney defects, hearing loss, or the development of inflammatory bowel disease may significantly impact the quality of life.
• Without these types of conditions, however, their life expectancy is normal.
• Support will be necessary to help an adolescent girl cope with body image issues and to help some women accept the fact that they will never be able to have children.

Sorce citiations

Schoenstadt, A. (2006, November 11). Prognosis for Turner Syndrome. Retrieved from http://genetics.emedtv.com/turner-syndrome/prognosis-for-turner-syndrome.html

Fallon, L. Fleming. "Turner Syndrome." The Gale Encyclopedia of Genetic Disorders. Ed. Brigham Narins. 2nd ed. Vol. 2. Detroit: Gale, 2005. 1297-1300. Gale Virtual Reference Library. Web. 12 Mar. 2011. Retrieved from http://go.galegroup.com/ps/i.do?&id=GALE%7CCX3451500431&v=2.1&u=scschools&it=r&p=GVRL&sw=w

Bosworth, Michelle. "Chromosomal Abnormalities." The Gale Encyclopedia of Genetic Disorders. Ed. Brigham Narins. 2nd ed. Vol. 1. Detroit: Gale, 2005. 249-255. Gale Virtual Reference Library. Web. 12 Mar. 2011.Rtreived from http://go.galegroup.com/ps/i.do?&id=GALE%7CCX3451500086&v=2.1&u=scschools&it=r&p=GVRL&sw=w

Jones, K.L. "XO Syndrome." Smith's Recognizable Patterns of Human Malformation, edited by Kenneth L. Jones and Judy Fletcher. 5th ed. Philadelphia: W.B. Saunders, 1997, pp. 81-87.

Monosomy X

by AM

Just extra info for you people who want to know more

By the time that she is 19 she will be only 5 feet tall

This is a effect on a women's/ child's height when she ages as yo can see the more she ages the less height she gains

Thanks for Watching

Webbed Neck linked to with Turners Sydrome

As you can see this female only has one X